[Clinical and histological indicators predictive of cervical metastases in laryngeal cancer].
INTRODUCTION: A study was made of possible clinical and pathological indicators associated with cervical lymph node involvement in laryngeal cancer. PATIENTS AND METHODS: Between 1994 and 1997, 85 patients with laryngeal cancer underwent surgery in the ENT department of the Complutense University of Madrid (Spain). A statistical analysis was made to identify clinical and pathological indicators of lymph node metastases. RESULTS: Predictive indicators (PI) of cervical metastatic disease in our study were: 1) tumor location; 2) low degree of differentiation; 3) invasion > 5 mm deep; 4) perineural invasion; and 5) invasion of the pre-epiglottic space.