[Osteosarcoma of the breast].
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Biomedical subjects
Publications and source records attributed to J Pirk.
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The present contribution compares the histologic and mechanic qualities of the vena saphena magna in man with the dog's vena jugularis. Both venae have a similar histologic structure and an analogous enzymatic equipment. The dog's vena jugularis has a smaller mechanic resistance, however, it is fast enough to resist the artery pressure. The dog's vena jugularis is therefore suitable for experiments with venae transplants which are reproducible in the clinical application.
The paper deals experimentally with the influence of the blood flow on the long-term fate of venous grafts in the arterial circulation. Based on the results of experiments, and applying the laws of haemodynamics, the paper provides evidence that the blood flow has a decisive influence on the behavior of the implanted vein. Veins with a mean flow of 364.5 ml/min, dilate by 70% while the external diameter of veins with a mean flow of 65.4 ml/min. remain without major changes. This difference in the behaviour is statistically significant at the 1% level. From the results ensues that the vein is suited for reconstructions where a blood flow of 50--200 ml/min. may be expected.