[Treatment of malignant pleural effusion with mepacrine chloride].
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Biomedical subjects
Publications and source records attributed to J Pillgram-Larsen.
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In a retrospective study the postoperative weight of one hundred prostatic adenomas was compared with the preoperative estimated size, based on rectal digital palpation. As a basis for the choice between transurethral and transvesical resection the adenomas were classified by digital palpation in three weight groups: less than 20 g. 20--40 g and more than 40 g. The objective was to avoid transvesical resection in small adenomas and transurethral resection in large ones, weighing more than 40 g. No adenomas weighing less than 20 g were removed transvesically. About one fourth of the adenomas removed transurethrally weighed more than 40 g. Forty-five per cent of the adenomas were placed erroneously into the 20 g group. Rectal digital palpation is a very unreliable method of assessing prostatic size, however, very small adenomas can be identified. Urethrocystoscopy can be of aid in identifying the very large ones.
Four cases of skin necrosis between vertical abdominal incisions are presented. Even though many years may elapse between the abdominal operations, necrosis of the skin as well as of the underlying fascia may develop between new and old vertical incisions parallel with each other. Such necrosis probably takes place particularly in patients with impaired peripheral circulation.
OBJECTIVES: Patients with sequelae from multiple trauma commonly display cognitive disturbances, specifically in the areas of attention and memory. This study was designed to assess cognitive functioning 3 years after severe multiple trauma and to investigate how cognitive performance is related to head injury severity and psychological distress respectively. METHODS: Sixty-eight multiple trauma patients were tested with a screening battery consisting of six neuropsychological tasks 3 years after injury. A measure of psychological distress (20-item General Health Questionnaire, or GHQ-20) was also administered. RESULTS: Patients who neither showed signs of reduced consciousness on admission to the hospital nor reported significant psychological distress at follow-up tended to have normal test performance. In five of the six tasks, cognitive impairment was related to the severity of the traumatic brain injury as measured by the Glasgow Coma Scale (GCS). In both attention span tasks, patients designated as cases by the GHQ had significantly lower scores than noncase patients. These bivariate relationships were upheld in multiple regression analyses, in which age, sex, and GCS and GHQ scores were entered as independent variables. When patients with severe head injuries were excluded from the analyses, GCS scores still contributed to the variance in tests of verbal attention span and delayed recall, but performance on attentional tasks was more strongly related to psychological distress than to GCS scores. CONCLUSIONS: Cognitive deficits in multiple trauma patients were related both to the severity of the traumatic brain injury and to the degree of psychological distress. The strength of the association between brain injury as indicated by GCS scores and cognitive performance differed between different tasks. Neuropsychological testing may assist in differentiating primary organic from secondary psychogenic impairments.