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Biomedical subjects

J Pilcher

Publications and source records attributed to J Pilcher.

29 records · Page 2Linked to original sources
PubMed1971

Clinical evaluation of perhexiline maleate in patients with angina pectoris.

This paper reports a double-blind trial of a new antianginal drug, perhexiline. Fifty-five patients suffering from angina pectoris were studied for periods of 12 or 24 weeks in a cross-over comparison against a placebo in four centres in the United Kingdom and Ireland. Perhexiline was effective in most patients as judged by reducing the number of anginal attacks in 84% and the consumption of glyceryl trinitrate tablets in 64%. The major side effect, dizziness, noted in one-third of the patients, may be dose/body-weight related. Perhexiline is a valuable new agent for the treatment of patients with angina, especially those who do not respond to other antianginal agents.

Adult↗
PubMed1970

Cor triatrium dexter.

A case of cor triatrium dexter is described in which the patient had been independently assessed in two cardiological centres as having a form of Ebstein's anomaly. The differential diognosis is discussed.

Adult↗
PubMedDate not supplied

Stability of long-term renal function in heart transplant patients treated with induction therapy and low-dose cyclosporine.

Long-term renal function was evaluated in heart transplant recipients who were treated with antilymphocyte globulin induction therapy and low-dose cyclosporine therapy. Although an initial 16% drop in the glomerular filtration rate occurred, long-term follow-up revealed stability of renal function. Four-year patient survival was 77.6%. Use of induction therapy with low-dose cyclosporine may preserve renal function without compromising long-term patient survival.

Antilymphocyte Serum↗