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Biomedical subjects

J Philippe

Publications and source records attributed to J Philippe.

At least 163 records · Page 9Linked to original sources
PubMed1979

Inhibition of degradation of insulin by ophthalamic acid and by a bovine pancreatic proteinase inhibitor.

We have previously observed that, on subcutaneous administration, a significant proportion of insulin is degraded at the site of injection. The present paper reports that the degradative activity of slices of rat adipose tissue can be inhibited in vitro by ophthalmic acid, a natural analogue of glutathione, and by bovine pancreatic proteinase inhibitor, whereas it is increased by the addition of reduced glutathione.

Adipose Tissue↗
PubMed1979

Chondromalacia patellae: a system of classification.

Degeneration of the cartilage on the under surface of the patella is shown to be the most frequent cause of "internal derangement of the knee" (63%). The axial view of the patellofemoral joint in 4 angles of flexion constitutes the procedure of choice for diagnostic exploration of patellar cartilage with, perhaps, the restriction for the medial compartment where arthroscopy is probably preferrable. The information obtained from single contrast arthrography of the patellofemoral joint has contributed greatly to the understanding of the sometimes confusing problem of chondromalacia of the patella. It has given an anatomic basis to the patellar syndrome and has served as a basis for a precise typographic system of classification. From this, we have been able to correlate localization and etiology which has then allowed logical solutions to be proposed for each group, based upon biomechanical considerations in both the frontal and saggital planes of the knee.

Cartilage Diseases↗