Biomedical subjects
Publications and source records attributed to J Petithory.
Serological studies made in a community of 106 pygmies led to 60% positive reactions with parasitic antigens, mainly of nematodes and trematodes. IgG and IgM levels are increased (about two times and four times the levels found in a normal population). These results prove the importance of these infestations by human or animal parasites in a tropical forest population.
A quality control in parasitology has been organized since 1977, under the direction of the Exotic Pathology Society. In 1978, more than 1 200 voluntary laboratories were participating. In 1979, according to the law of the eleventh of July 1975, this control is going to be obligatory for the 3 750 public or private laboratories effecting parasitologic tests. That should improve the quality of these tests, outside any repressive aspect.
Report of the case of a six-year-old child who presented a meningitis with 40 % eosinophils in the cerebrospinal fluid and which spontaneously regressed. These clinical data and the serologic (positive test for many nematod antigens) and epidemiological findings (presence of Angiostrongylus larvae in terrestrial gasteropod) lead to the conclusion that we were in presence of the first case of eosinophil meningitis due to Angiostrongylus cantonensis reported in the island of la Réunion.
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We have studied false reactions in hydatic serology in order to improve its value. We have found false positive reactions in two cases of tumor (hepatic sclerocholangiomatosis and pleural mesothelioma) and among children showing cor's milk protein intolerance when serum is tested with an antigen extracted from ox's lung. As for false negative reactions, they are scarcely due to circulating antigens. We have found, for 34 falsely negative serums, IgG, IgM and above all IgE levels lower than the levels of patients showing a positive serology.