Search PubMed⌕ Search

Biomedical subjects

J Pemberton

Publications and source records attributed to J Pemberton.

At least 55 records · Page 3Linked to original sources
PubMed1980

A prospective study of the development of coronary heart disease in a group of 1202 middle-aged men.

A prospective study of the development of coronary heart disease (CHD) in men aged 45--54 was conducted in six group practices in Belfast, Northern Ireland Of the 1343 men examined once by clinical, electrocardiographic, biochemical and anthropometric methods, 1202 free from CHD entered the prospective study. All 1202 men were followed for at least five years and the average annual incidence of CHD during this period was estimated as 1.73% (104 men developed). Of the 28 measurements made at initial examination, four--S-T depression, total lifetime tobacco consumption, diastolic blood pressure, and height (significant on classical linear discriminant function analysis)--were investigated in more detail. Using multidimensional contingency table methods, the probability of developing CHD was found to depend, in rand order of importance, on S-T depression, total lifetime tobacco consumption, and diastolic blood pressure. The risk of development was maximal (0.3732, four times the 'random' risk) in men with S-T depression, greater than average total lifetime tobacco consumption, and a diastolic pressure of 100 mm Hg or more.

Analysis of Variance↗
PubMed1977

Some behavioural changes in 493 patients after an acute myocardial infarction.

A retrospective study of behavioural changes in 493 consecutive patients who had survived a first acute myocardial infarction was carried out. The changes in behaviour that were studied related to smoking, physical activity, and weight loss. The personalities of the patients were also studied by means of the Eysenck personality inventory to find out if there was any relationship between the personality factors, extroversion and neuroticism, and the changes in behaviour. Sixty-six per cent of the men and 59% of the women reduced or stopped smoking, 60% of the men and 81% of the women reduced their physical activity, and 67% of the men and 56% of the women lost weight. Some significant associations were found between these changes and the medical advice given, the patients' views of the value of the change in behaviour, and the severity of the illness. Personality factors as assessed were not associated with any of the observed changes, except in the case of physical activity. Those who increased or decreased their physical activity had a significantly higher mean neuroticism score than those who did not change their behaviour in this respect.

Adult↗
PubMed1975

Pulmonary fungal infection complicating treated malignant disease.

Secondary pulmonary fungal infection in patients being treated for malignant disease may be difficult to diagnose. Nine patients are described, illustrating some of the possible radiological appearances. There was pathological support for the diagnosis in seven of these patients. A plea is made for a higher level of suspicion in patients with the predisposing factors who also develop pulmonary complications so that suitable treatment may be given, even though sputum examination is negative.

Adult↗
PubMed1969

William Pickles.

Explore the source record for details and available documents.

England↗
PubMed1968

Duration of last attack in 998 fatal cases of coronary artery disease and its relation to possible cardiac resuscitation.

All the deaths attributed to coronary artery disease and occurring in Belfast during one year were studied.The frequency distributions of the cases by interval of time between onset of the last attack and death are given for those not admitted to hospital, for those admitted to hospital, and for those already in hospital for some other cause of illness.Sixty per cent. of all the deaths occurred outside hospital. This indicates that the problem of cardiac resuscitation in coronary artery disease is to a considerable extent an extra-hospital one.Twenty-seven per cent. of the men and 22% of the women died within 15 minutes, but the median period of survival was 3 hours 30 minutes for men and 6 hours 18 minutes for women.The median time interval from the onset of the attack to sending for medical aid was 1 hour 17 minutes for men and 1 hour 6 minutes for women, and from summoning medical aid to sending for the ambulance 59 minutes for men and 1 hour 26 minutes for women. Ninety-six per cent. of the ambulance journeys to the patient were accomplished in less than 20 minutes.It was found among men, but not among women, that the duration of survival tended to be longer in older patients and in second or subsequent attacks.Of the 596 who did not gain admission to hospital 229 (23% of all the 998 patients) were known to have survived for more than half an hour after the onset of the fatal attack; 182 (18%) survived for more than one hour; and 143 (14%) survived for more than two hours. It is among these that there would appear to be special scope for the cardiac ambulance, providing that medical aid is sought and the ambulance is summoned without delay.

Adolescent↗