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Biomedical subjects

J Pecker

Publications and source records attributed to J Pecker.

At least 37 records · Page 2Linked to original sources

[Lateral interscalenic approach for tumors of the cervical intervertebral foramina (author's transl)].

The authors report six cases of tumours limited to the cervical inter-vertebral foramen. The patients presented with cervico-brachial neuralgias occasionally accompanied by radicular sensitivo-motor impairment. Radiographs and tomographs of the cervical spine demonstrated enlargement of the intervertebral foramen with bone proliferation depending on the etiology and provided in easy diagnosis in all the cases. A myelogram showed the absence of extension into the spinal canal thus allowing distinction from the group of dumbell tumors. In the six cases vertebral angiography gave information regarding the vascularisation and relationships of the tumour. The histological diagnosis was different in each case : neurofibroma, chordoma, osteochondroma, osteoma, osteoblastoma and an aneurysmal bone cyst. The same surgical approach was used in the six cases. Neither a laminectomy with facettectomy, nor a classical antero-lateral approach allow for a satisfactory exposition of the tumor. On the contrary a lateral interscalenic approach including dissection of the brachial plexus lead to a trouble free excision. This approach was precised by anatomical dissections.

Adolescent↗

[Nerve grafts. Experimental study. Importance of number of suture points (author's transl)].

An experimental study about 36 nervous grafts on laboratory rats is reported. This study emphasizes the interest of microsurgical technique and, further more, the role of the number of stitches improving the results of each anastomosis and, thus, the quality of neural regeneration. In each animal, after sectioning tibial nerve, a graft (sciatic nerve same side) is interposed and sutured in three different ways; in a first lot of animals 6 stitches at the level of each anastomosis; in a 2nd lot: 2 stitches and in a 3d one a single stitch. The animals are tested at the end of the 20th week, with an electrophysiological control before being sacrified. The pathological controls take in account the number of regenerated nervous fibers below the graft. Our study confirm the superiority of results in the 6 stitches lot. The authors emphasize the role played by a watertight suture to prevent an anarchic growth of regenerating axones outside the graft.

Animals↗

Treatment in tumours of the pineal region: value of sterotaxic biopsy.

The treatment of tumours of the pineal region is the subject of keen controversy between advocates of surgical excision and those of radiotherapy with ventricular shunting. The proponents of these extremes often seem to ignore the wide pathological variety of tumours of this site. Attempted excision of a germinoma invading the walls of the 3rd ventricle is as futile and dangerous as irradiation of a teratoma. Stereotaxic biopsy provides precise pathological diagnosis and thus allows more specific management; the procedure is safe and no serious complications were experienced in 25 cases.

Adolescent↗

Stereotaxic exploration in 200 supratentorial brain tumors. Its value in addition to computerized tomography.

The authors emphasize the advantages of stereotaxic methodology in the management of 200 brain tumors. Nowadays computerized tomography is the first stage of radiologic diagnosis. Both CT scan and stereotaxic examination have been carried out in more than 35% of these tumors. Rather than a comparison of the two examinations, the authors' purpose is to attempt to demonstrate their complementarity in the assessment of location, volume, and nature of the lesion and eventually in the choice of a therapeutic attitude. Analysis of topographic data and staged biopsies, gathered from the 'stereotaxic space,' provides the neurosurgeon with accurate information for planned surgical excision or interstitial irradiation.

Brain Neoplasms↗

[Contribution of stereotactic methods to diagnosis and treatment of tumors of the pineal region (author's transl)].

The respective role of surgical ablation versus palliative methods (i.e. shunting followed by irradiation) in the treatment of tumors of pineal region is still questionnable and must take into account the variability of their pathology. Thus, knowledge of tumoral type in each case is the first step to therapeutic discussion. The stereotactic methods allow a faithful biopsy, easy to interpret and without major risks.

Adolescent↗

Role of the pneumo-encephalogram in the diagnosis of spontaneous subarachnoid haemorrhage.

The authors have collected eighteen cases of primary intraventricular lesions revealed by a subarachnoid haemorrhage. Among these cases, the most important are the choroid plexus papillomas followed by ependymomas; some cases have no precise histological interpretation. Generally speaking, cerebral arteriography gives only indirect evidence of ventricular dilation and thus does not confirm the presence of a lesion. On the contrary, the pneumoencephalogram is consistantly positive, but does not give the differential diagnosis between intraventricular tumours and primary intraventricular haemorrhages. This test should therefore be given the same importance as spinal cord arteriography in the exploration of subarachnoid haemorrhages with negative cerebral angiograms.

Adolescent↗

X-linked hydrocephalus, with aqueductal stenosis, mental retardation, and adduction-flexion deformity of the thumbs. Report of a family.

A new family is reported of a Bickers-Adams-Edwards syndrome. This family has been studied up to three generations. Two female carriers are known. Among the six male children who are affected, four are severely mentally retarded, have spasticity of the legs, and survived with a mild macrocephaly, and two show a more severe and rapid progression of head enlargement. A partial aqueductal stenosis, with remarkable ventricular dilatation, has been demonstrated by pneumoence-phalography in three boys. A deformity of the thumbs links these six children together. One of them has been treated by a ventriculoperitoneal shunt, when 18 months old, without any improvement in the neurological condition. The mental deficiency is much more severe than could be expected from the degree of hydrocephalus, at least as estimated clinically by the macrocephaly. Hydrocephalus is precocious, and the ventricular dilatation very advanced when seen by PEG studies. Recognition of the female carriers is not possible.

Adolescent↗

[Tumors of the carotid body. Diagnostic and therapeutic considerations. Apropos of a case].

The authors report a new case of carotid body tumour operated on, in a 26 year old woman. Recalling the main clinical and histological characteristics of these tumours, they emphasize the importance of pre-operative assessment and the decisive value of arteriography. Modern techniques of surgery of the carotid bodies permit one to face the risk of damage during removal. They re-emphasize the necessity of surgical treatment able to ensure a cure. Finally, emphasizeing the special gravity of advanced tumours (group III), they condemn a conservative attitude and recommended operation as early as possible.

Adult↗