Search PubMed⌕ Search

Biomedical subjects

J Pasternak

Publications and source records attributed to J Pasternak.

93 records · Page 6Linked to original sources

[Evaluation of the eventual activity of cyclosporin A in preventing the transmission, by blood transfusion, of Trypanosoma cruzi infection].

Cyclosporin A has activity "in vitro" against trypomastigotes of Trypanosoma cruzi. We tried to evaluate, in an "in vitro" model, using variable concentrations in whole blood contaminated with known numbers of parasites and injecting this blood after a two hour incubation period in mice if it was possible to prevent infection. In this model the drug, in the concentrations used, was unable to prevent infection.

Animals↗

[Aorto-enteric fistula as a rare manifestation of rupture of an abdominal aortic aneurysm--case report].

Aortoenteric fistula represents a communication between aortic and duodenal lumen. It is a very rare complication of aortic aneurysmal disease as well as aortic prosthetic surgery. There are only few surgeons who have seen more than one case of aortoenteric fistula. At the Institute of Surgery one case of aortoenteric fistula was treated. It was well diagnosed at the Institute for Internal Medicine, and then presented to the vascular surgeon who operated immediately. The whole diagnostic and therapeutic procedure was well done, but stenosing carcinoma of ascendent colon was found during the operation. Resection were done leading to the dehiscence of bowel anastomosis and fatal outcome for the patient. This case is instructive in a diagnostic and surgical manner.

Aortic Aneurysm, Abdominal↗