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Biomedical subjects

J Passchier

Publications and source records attributed to J Passchier.

132 records · Page 8Linked to original sources

The effect of stress imagery on arousal and its implications for biofeedback of the frontalis muscles.

The purpose of this study was to determine whether the frontal muscles of the forehead during the imagination of an individualized stress situation reflect general arousal. Physiological arousal and subjective feelings of tension were measured during a stress and a relaxing imaginative situation, utilizing a counterbalanced design. Frontalis EMG during stress imagination was raised and was paralleled by more reported tension, elevated skin conductance, and trends toward increments in heart rate and respiration rate. The raised frontalis EMG can be seen as a consequence of the greater effort spent in the stress imaginative situation than in the relaxing one. This experiment supports an important assumption of the clinical application of frontalis EMG biofeedback to stress-related disorders. Other assumptions still remain to be examined.

Adolescent↗

Organismic, stimulus and task determinants of phasic and tonic heart rate and skin conductance changes.

The effects of three variables (perceptual style 'leveling--sharpening', stimulus intensity and task) on tonic and phasic heart rate and skin conductance responses were studied. 24 levelers and 24 sharpeners received a series of 25 auditory stimuli under two instructions (task): in one task subject had to listen carefully to possible small differences between tones (intake task) and in the other task the subject had to count back silently and could neglect the tones (rejection task). One third of each group received tones of 50 dB, one third 75 dB and one third 100 dB. Results show that task has a strong effect on tonic responses in the direction predicted from Lacey's intake--rejection hypothesis. There is hardly any effect of task on phasic responses: only at the first trial heart rate tends to decelerate more in the intake than in the rejection task. Stimulus intensity does not influence tonic responses but very strongly affects phasic responses: deceleration to 50 and 75 dB, acceleration to 100 dB. GSR amplitude increases monotonically as a function of stimulus intensity. There is no difference between levelers and sharpeners with regard to tonic responses. Concerning phasic heart rate, sharpeners decelerate more than levelers and levelers have greater GSRs than sharpeners. It is suggested that tonic changes are relatively more under cognitive control, whereas phasic changes are more of a non-cognitive reflex-like nature. A relationship between the distinction arousal-activation as proposed by Pribram and McGuinness (1975) and the results of this experiment was suggested.

Acoustic Stimulation↗

Chronic pain and its impact on quality of life in adolescents and their families.

OBJECTIVE: To study chronic pain not caused by somatic disease in adolescents and the effect of pain on the quality of life of the adolescents and their families. METHODS: One hundred twenty-eight youngsters (12-18 years) who had reported chronic pain kept a 3-week diary of their pain and completed a questionnaire on quality of life. Their mothers completed a questionnaire on the impact of their youngster's pain on the family. RESULTS: The most prevalent pains were limb pain, headache, abdominal, and back pain. The pain increased during the day, with the highest frequency around dinner time and the highest intensity around bedtime. Girls reported more intense and more frequent pain than boys. The higher the intensity and frequency of the pain, the lower the self-reported quality of life of the female or male adolescent, especially regarding psychological functioning (e.g. feeling less at ease), physical status (a greater incidence of other somatic complaints), and functional status (more impediments to leisure and daily activities). Chronic pain also had a negative impact on family life. The mothers reported restrictions, particularly in social life, and problems dealing with the stress of the adolescent's pain. CONCLUSIONS: Chronic pain, not caused by somatic disease, was present to a higher degree in girls; the pain increased during the day and had a negative impact on quality of life of the adolescents and the family. There is a need for future research aimed at identifying risk factors for chronic pain and pain-associated quality of life in children and adolescents.

Adolescent↗

Prediction of quality of life after coronary artery bypass graft surgery: a review and evaluation of multiple, recent studies.

OBJECTIVE: To review studies predicting psychosocial outcome after coronary artery bypass graft surgery (CABG). METHODS: Seventeen prospective studies, appearing in the MEDLINE and PsycLIT data bases between 1986 and 1996, were reviewed regarding objectives, methodological issues, results, and clinical relevance. RESULTS: All studies reported that psychological factors bad predictive value. In particular, preoperative anxiety and depression predicted postoperative psychological maladjustment; social support, preoperative feelings of control, denial, and optimism contributed to psychological adjustment. CONCLUSIONS: Many specific psychological outcomes seem to be best predicted by preoperative assessment of functions in that specific area, especially in the case of anxiety and depression. Furthermore, personality factors including denial, optimism, control, and the need for support appear to be predictors of psychological outcome. Appropriate identification of predictive factors might improve the development of individually tailored interventions for patients at risk of postoperative psychological problems.

Adult↗

Course of distress experienced by persons at risk for an autosomal dominant inheritable disorder participating in a predictive testing program: an explorative study. Rotterdam/Leiden Genetics Workgroup.

OBJECTIVE: To compare the effects of predictive DNA testing on participants at risk for either Huntington disease (HD), or familial adenomatous polyposis (FAP), or hereditary breast and ovarian cancer (HBOC). METHOD: Psychological distress was measured with the Impact of Event Scale before testing and at 1 week and 6 months after the test result, in individuals at 50% risk for either HD (N = 25), FAP (N = 23), or HBOC (N = 10). RESULTS: A marginally significant trend was found indicating that carriers of the disease genes tended to show unchanged levels of distress during the study period whereas noncarriers showed the expected decrease. Men reported significantly less distress than women, and 1 week after the test result male noncarriers showed a sharp significant increase in the reported distress followed by a steady decline up to 6 months later. CONCLUSIONS: The course of distress over time reported by carriers and noncarriers of the three disease genes was similar, which leads one to conclude that the previous experience with predictive testing for Huntington Disease may be a useful paradigm. However, those formerly at risk for HD reported more distress than those at risk for FAP and HBOC. From our clinical experience we learned that individuals at risk for FAP and HBOC are more inclined to ward off the emotions involved. Additional qualitative studies should be undertaken to investigate this.

Adult↗

Age migraine and achievement motivation related? A psychophysiological study of responses to real-life achievement stress in young headache sufferers.

Achievement motivation and its physiological correlates were studied in 37 young migrainous headache sufferers (30 females and 7 males) and in 37 matched controls. Temporal and digital pulse amplitude, the EMGs of the m. frontalis, anterior temporalis and corrugator supercilii, heart and respiration rate, head temperature and electrodermal activity were measured during an adaptation session, an examination and an intelligence test. An abnormal response in the temporal artery, which was present in the migrainous headache sufferers, was not associated with achievement motivation. But the latter was positively associated with a high skin conductance level, a greater number of spontaneous skin conductance responses (SCRs) during the examination and a lower digital pulse amplitude in both the migrainous headache and control groups. Higher sympathetic activity in subjects with high achievement motivation was interpreted as an indication of greater mental effort and is a possible contributory factor to an attack in those with migraine.

Achievement↗