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Biomedical subjects

J Pasquier

Publications and source records attributed to J Pasquier.

131 records · Page 8Linked to original sources
PubMedDate not supplied

[Acromegaly and sleep apnea syndrome (author's transl)].

Acromegaly associated with a Sleep Apnea Syndrome has but exceptionally been reported. Polygraphic recordings of sleep have been carried out in parallel with the determination of pituitary hormonal secretions, during the nycthemeral period before and after surgical treatment of the adenoma. There appears a Sleep Apnea Syndrome of the predominant obstructive type; the Apnea index is: 57 (N less than or equal to 4); the hypnogram is considerably jagged, with more than a thousand wakings and changes in the sleep stages, due to a great number of apneas. The deep slow sleep never occurs: no stages 3 and 4. The physiological peak of G.H. secreted in the beginning of the deep slow sleep thus does not appear in the Sleep Apnea Syndrome. The existence of a "false negative" criteria of a cured Acromegaly must be taken into consideration. The Sleep Apnea Syndrome must be differentiated from Narcolepsy and the usual Pickwickian syndrome. The Sleep Apnea Syndrome and Acromegaly seem to be two separate diseases, each one evolving independently. The cure of Acromegaly has not led to the cure of the Sleep Apnea Syndrome and the latter has not prevented the clinical and biological cure of Acromegaly. This may be an argument in favor of the independence of Acromegaly towards some hypothalamic structures.

Acromegaly↗
PubMedDate not supplied

[Preoperative approach to the histologic diagnosis of cerebral tumors by combination of clinical and paraclinical examinations (EEG, computerized cerebral tomography, scintigraphy, and angiography)].

The authors present their last series of one hundred operated cerebral tumors (19 meningiomas, 16 benign gliomas, 38 malignant gliomas, 20 isolated metastasis, 8 diversified tumors) studied on the clinical, E.E.G., isotopic scanner, computorized tomographies and angiographic point of view. The comparison of these multiple exams, permits one to determinate the malignant of benign nature of a tumor in 86 p. 100 of the cases and the precise histological nature in 56 p. 100 of the cases. The biopsy effectuated in stereotaxic conditions permits to solve the problem in uncertain cases. The interest of computorized tomography is emphasized (discovery or confirmation of a suspected tumor, definition of its extension in depth), but this recent technic is incapable of constant confirmation of the histological diagnosis; it cannot replace other confirmed methods of diagnosis. The angiography remains necessary to guide the surgical gesture.

Brain Neoplasms↗