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Biomedical subjects

J Pannek

Publications and source records attributed to J Pannek.

61 records · Page 4Linked to original sources

The Lithovac: new suction device for the Swiss Lithoclast.

Minimal invasiveness characterizes modern stone therapy. Several years ago, we presented the Swiss Lithoclast, a ballistic system for endoscopic stone therapy. Its disintegrational power is superior to that of the other intracorporeal lithotripsy devices, and it has gained great recognition. Now, special probes (Lithovac) have been developed to combine lithotripsy with suction. These probes differ in width (1.6, 3.5, or 4 mm) and length depending on the intended location of use (kidney, ureter, bladder). The probes were tested in a standardized stone model. The variable suction energy counteracts the propulsive energy of the Lithoclast. Clinical experience could be gained with stones in the urinary bladder, Kock pouches, the ureter, and the kidney. There were no complications related to either the Lithoclast or the Lithovac. In staghorn stones, small (< 2 mm) pieces could be removed easily during lithotripsy. Fragments as large as 3.5 mm could be evacuated with the Lithovac after removing the Lithoclast probe. Using the suction, clear vision could be achieved (especially useful in struvite stones). In the ureter, a learning curve had to be overcome to balance fluid inflow and suction pressure. Otherwise, the ureter may collapse. However, this was possible in all patients. Using the single-shot mechanism, stones were broken up fast. The fragments could be dragged to the Lithoclast probe with the Lithovac. No pushback happened. In bladder and Kock pouch stones, suction may not be enough to hold the stone to the probe, but it is of great value to keep a small volume in the bladder/pouch and still have excellent visibility. The Lithovac is a useful tool in all endoscopic applications of the Lithoclast.

Endoscopy↗

Surgical management of Wilms tumor with intracardiac neoplastic extension.

In the management of Wilms tumor (nephroblastoma) with intracardiac extension (ICE) an interdisciplinary approach is mandatory. The three cases reported here reflect the impressive improvements of both diagnostic facilities and surgical strategies over the last 16 years as evidenced in the literature. Nowadays, prerequisite for a well-planned, safe, and successful operation is the exact delineation of the intravasal tumor extension and the use of the combined techniques of cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest (DHCA). In the first child (1976) only tumor nephrectomy was performed. Under chemotherapy fatal massive pulmonary embolism occurred. In the second child (1980) ICE was removed after tumor nephrectomy on an emergency basis using CPB. The third child (1987) was operated on electively using the concepts of CPB+DHCA. Now, both children are doing well without evidence of disease 13 years (case 2: stage III) and 6 years (case 3: stage IV) after an aggressive adjuvant-therapy regimen of multiagent chemotherapy and radiation. In conclusion, in children with nephroblastoma and ICE an aggressive surgical approach and subsequent multiagent chemotherapy are advocated.

Chemotherapy, Adjuvant↗

Wilms tumor with intracardiac neoplastic extension.

A rare case of a Wilms tumor with intracardiac neoplastic extension is presented. The good prognosis of even extensive nephroblastoma is the reason for attempting a radical surgical approach to patients with intracardiac tumor thrombus. The exact preoperative delineation of the intracasal tumor extension is essential for a safe and successful operation. Ultrasonography in combination with echocardiography is the preferred modality for detecting intracardiac extension.

Child, Preschool↗

Rupture of ileal neobladder due to urethral obstruction by mucous plug.

We report a case of ileal neobladder rupture after radical cystectomy due to mucus obstruction of the bladder neck. Since mucus production in bowel neobladders cannot be sufficiently influenced pharmacologically, patients with a continent urinary diversion connected to the urethra should learn self-catheterization.

Humans↗