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Biomedical subjects

J Palmer

Publications and source records attributed to J Palmer.

At least 253 records · Page 14Linked to original sources
PubMed1983

Pregnancy in patients with cystic fibrosis.

As more patients with cystic fibrosis reach adulthood, questions arise about the potential hazards of pregnancy. We reviewed the medical records of eight women with cystic fibrosis who had a total of 11 completed pregnancies and had been evaluated within 1 year before conception. In five women (Group 1), the overall maternal condition was little affected by the pregnancy, and in three women (Group 2), the mother's condition deteriorated during and after pregnancy and did not return to the pregravid state. With regard to pregravid status, significant differences between patients in Group 1 and Group 2 were found in Shwachman-Kulczycki clinical scores, weight for height values, Brasfield chest radiograph scores, and pulmonary function. A quantitative assessment of pregravid nutritional and pulmonary status is useful in counseling women with cystic fibrosis about the risk of pregnancy.

Adolescent↗
PubMed1983

Multiple-view scintigraphy for localization of osteoid osteoma.

A circumscript accumulation of 99mTc-MDP in the spine of a patient, presenting with back pain and negative radiographs, was histologically confirmed to be an osteoid osteoma. As radiological procedures failed to localize the lesion, this was accomplished by means of posterior and lateral view bone scintigrams as well as by single photon emission tomography. The role of scintigraphy in patients suspected of having osteoid osteoma and the possibility of localizing the lesion before and during surgical intervention are underlined.

Adult↗
PubMed1983

Report of a double-blind crossover study of flurbiprofen and placebo in detrusor instability.

Thirty-seven elderly patients with idiopathic detrusor instability attending St. Pancras Hospital were entered into a double-blind crossover study of the prostaglandin synthetase inhibitor flurbiprofen (50 mg four times a day) and placebo, and twenty-seven patients completed the crossover. Flurbiprofen was significantly better than placebo in increasing the maximum contractile pressure. Flurbiprofen also significantly reduced the total number of voids and the number of urgent voids compared to baseline. Those patients whose volume to first contraction at baseline was less than 100 cm3 had further significant beneficial effects with flurbiprofen (increased volume at first sensation, volume at first contraction and total bladder capacity). Significant beneficial effects of placebo treatment (compared to baseline) were found for volume at first sensation and volume at first contraction, but only in those patients whose volume to first contraction at baseline was less than 50 cm3 and 100 cm3, respectively.

Aged↗
PubMed1983

Survey of the demographic characteristics of patients requiring restraints in a psychiatric emergency service.

This paper examines the previously studied topic of the prevalence of uncontrollable behavior in psychiatric emergencies, using the need for restraints as an indicator, and seeks to discover demographic characteristics that were associated with patients needing restraints. The variables considered are sex, referral source, marital and financial status, race, education, diagnosis, age, and disposition. The findings of this survey were compared with those of another survey, which was conducted with a different population in a different community context, using tendency toward assault as an indicator of uncontrollable behavior. Although the two surveys were not strictly comparable, some interesting points were raised regarding differences and similarities.

Adolescent↗
PubMed1982

A scintillation camera technique for measurements of the reticuloendothelial function - comparison of different methods for measuring RES function.

A highly standardized 99mTc-sulphur colloid was used to evaluate reticuloendothelial system (RES)-function in the normal rat and after RE blockade by gelatin (Haemaccel). Activity distribution in the animals was measured with a scintillation camera technique. Total uptake of activity in the liver was estimated. From the time-activity curves over the liver, the phagocytic index (kphag) was evaluated. Estimation of the uptake rate of the labelled colloid into the liver and into other parts of the RES was also performed using a two-compartment model. Different methods of evaluation of RE function were compared. It was shown that for a proper estimation of the RE function, the whole uptake curve must be considered. Gelatin (Haemaccel) significantly reduced the total colloid uptake by the liver. The colloid uptake rate into the liver was also significantly reduced. Liver specimens after colloid injection were examined by light and electron microscopy showing vacuolation of hepatocytes and sinusoidal cells probably due to pinocytosis. The technique described enables functional studies of the RES. It has the advantage of noninvasive registrations and is based on the same technical facilities as used for routine liver scintigraphy.

Animals↗
PubMed1981

Scintigraphic evaluation and dynamic studies with thallium-201 in thyroid lesions with suspected cancer.

Scintigraphic studies of the thyroid with thallium-201 chloride were performed in 46 patients in whom the final diagnosis was established by histology. In dynamic studies of 36 patients, sequential imaging was performed the first 40 min after injection. A single exponential, Cexp(-lambda t), was fitted to each of the curves generated from apparently pathological and from normal regions in each patient, as determined by earlier conventional scintigrams. To minimize the effects of normal individual variations, the relation between pathological (p) and normal (n) regions in the same patient was emphasized and quantified by two parameters, namely the extrapolated zero-time intercept (Cp/Cn) and the time development (lambda p-lambda n) of the ratio of counting rates/unit area in the two regions. The turnover appears to be somewhat slower for pathological tissue than for normal tissue. Although this difference was significant on the 5% level for both cancer and adenoma as a group, only the relative disappearance rate (lambda p-lambda n) resolved cancer frm adenoma and from goiter on the same level. All but one of the differentiated cancers had an increased uptake.

Adenocarcinoma↗
PubMed1980

Cysticercosis of the fourth ventricle: a report of two cases.

Cysticercus cellulosae, the larva of the pork tapeworm, has a predilection to encyst within the central nervous system. It is common in endemic areas, such as Central and South America, but rare in Australia. The clinical and radiological findings in two patients with fourth ventricular cysts are described.

Adult↗
PubMed1978

Chylous ascites following retroperitoneal lymphadenectomy: report of 2 cases with guidelines for diagnosis and treatment.

Two cases of chylous ascites following retroperitoneal lymphadenectomy are presented. The first case, a 3-year-old girl, undersent a right radical nephrectomy and retroperitoneal lymph node dissection for Wilms' tumor. Chylous ascites developed postoperatively and resolved after 3 months of supportive therapy. The second case, a 45-year-old woman, underwent a right radical nephrectomy and retroperitoneal lymph node dissection for renal carcinoma. Chylous ascites occurred postoperatively and resolved after a single paracentesis. Diagnosis, evaluation, and therapeutic modalities are outlined and the literature is reviewed.

Adenocarcinoma↗
PubMed1978

Panniculectomy and the difficult ileostomy for urinary diversion.

This paper describes a helpful operation for revision of the difficult ileal stoma for urinary diversion. By using the standard technique of panniculectomy or abdominal lipectomy, the ileal loop can be left in the same position on the abdominal wall and healthy, viable tissue can be mobilized and repositioned to enable the urological surgeon to perform the cutaneous portion of the procedure again and to refashion the ileal loop. This saves the patient an operation of greater magnitude and risk.

Abdominal Muscles↗
PubMed1978

Meconium screening for cystic fibrosis.

In our hands, the BMC-Test Meconium has been a significant step towards the goal of developing an ideal newborn screening test for CF. It is easily performed, is highly specific, has reasonably high sensitivity, and--given its limitation of identifying only patients with CF who have intrauterine pancreatic insufficiency--is the best method of screening newborns for CF that has been devised to date. Many technical problems remain to be solved before the test can be endorsed without reservation. Because the test, as currently constituted, does not identify all potential subjects for further testing who might have CF, it should not be made mandatory. It is, however, better than other available screening methods for CF and can be praised for that benefit. The concept has indicated a valuable new direction for mass-screening possibilities and perhaps can, by future modification, be made sensitive enough to warrant universal usage.

Albumins↗