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Biomedical subjects

J P Raynauld

Publications and source records attributed to J P Raynauld.

10 recordsLinked to original sources
PubMed1992

The health assessment questionnaire 1992: status and review.

Over 100 papers describing and utilizing the Stanford Health Assessment Questionnaire (HAQ) have been published since 1980. A brief overview of the HAQ is presented along with a guide to the accumulated literature. The topics covered include: studies using the disability, pain, economic, and drug side effect dimensions of the HAQ; reliability and validity studies; applications to various rheumatic diseases; language adaptations; modifications and derivative scales; studies correlating the HAQ with sociodemographic, health status, laboratory, and physical measures; and randomized controlled trials and observational studies using the HAQ. A few comments regarding future directions for research are also presented.

Arthritis↗
PubMed1992

[A simplified terminology for abnormalities of the lumbar disks].

The terminology for abnormalities of the lumbar disk has always been a source of confusion. Recent advances in pathological studies have inspired the authors to propose a simple classification of common disk anomalies suitable not only for diagnostic radiologists but also for referring clinicians. Although the diagnosis of a few pathological entities will only be possible with specific imaging techniques, the proposed classification is appropriate for reporting observations from plain films, conventional tomograms, myelograms, discograms, computed tomography scans and magnetic resonance images. All lumbar disks can thus be classified into one or more of the following categories: normal, aging, scarred, ruptured and herniated. A disk herniation is defined as a localized exit of disk material beyond the limits of the original intervertebral space.

Adult↗
PubMed1991

A simplified terminology for abnormalities of the lumbar disk.

The terminology for abnormalities of the lumbar disk has always been a source of confusion. Recent advances in pathological studies have inspired the authors to propose a simple classification of common disk anomalies suitable not only for diagnostic radiologists but also for referring clinicians. Although the diagnosis of a few pathological entities will only be possible with specific imaging techniques, the proposed classification is appropriate for reporting observations from plain films, conventional tomograms, myelograms, diskograms, computed tomography scans and magnetic resonance images. All lumbar disks can thus be classified into one or more of the following categories: normal, aging, scarred, ruptured and herniated. A disk herniation is defined as a localized exit of disk material beyond the limits of the original intervertebral space.

Aging↗
PubMed1987

Micropipette holders: vented types are preferable to closed types.

Due to the large coefficient of volume expansion of water with temperature, the use of closed micropipette holders results in significant pipette motion and pressure ejection of electrolytes or marker dyes as the temperature of the pipette goes up upon insertion in the CNS or spinal cord of warm blooded preparations.

Iontophoresis↗
PubMed1987

The silver-silver chloride electrode: a possible generator of offset voltages and currents.

Large input currents can be generated by an asymmetry in the chloride activity seen by Ag-AgCl electrodes used at the input of intracellular amplifiers because offset compensation no longer takes place at the input of the amplifier but rather later in the circuit in many modern amplifiers. This situation occurs when chloride-free solution, such as potassium acetate, potassium citrate or various intracellular dyes are used as pipette and electrode holder filling solutions. Omitting the agar bridge at the reference electrode, or using a platinum electrode will have similar results. Values of cellular membrane potentials can be significantly contaminated under such conditions, particularly where the amplifier input resistance did not exceed 10(10) omega and where small cells were studied. Unexpected iontophoresis of Cl- can occur when the asymmetry is such as to make the recording pipette negative. These offsets can be avoided in all situations by the use of salt bridges which insure that the two Ag/AgCl junctions are in contact with Cl- of the same activity.

Electrophysiology↗
PubMed1986

Thermal stability of hydrolic drives.

The thermal stability of hydrolic drives is investigated theoretically and experimentally. A commonly used model is found to have a positive positional temperature coefficient of 7 microns per degrees C at 22 degrees C. A simple temperature compensator is described. This should lead to improved intracellular recording stability when recording from small cells.

Microelectrodes↗
PubMed1972

Goldfish retina: sign of the rod input in opponent color ganglion cells.

After light adaptation, all "on-center" ganglion cells in the dark became "red on-center," and all "off-center" cells turned into "red off-center" cells. On a chance basis, this similitude of effect between the rods and the red cones in opponent color cells was not expected. These findings indicate that in the goldfish there is some similarity between the connections of the rods and of the long-wavelength cones.

Adaptation, Physiological↗