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Biomedical subjects

J P Kuiper

Publications and source records attributed to J P Kuiper.

At least 19 recordsLinked to original sources
PubMed1994

Age-related changes in wound healing.

Knowledge of the physiology of wound healing, in particular the recovery of the dermal and epidermal compartments and the co-ordination of these processes by the cytokine network, is of great importance to rational wound management. The individual components of the wound healing process have been studied using various in vitro and in vivo models, comparing young, adult and aged individuals. Many of the processes involved in wound healing are impaired in the elderly. However, in elderly patients not suffering from concomitant diseases, the rate of wound healing is normal or only slightly reduced. Various 'systemic factors' (endocrine and haematological diseases, nutritional deficiencies and medications) and 'regional disorders' (vascular and neural diseases) may impair wound healing. These complicating conditions occur more frequently in aged subjects. Failure of wound healing in the elderly is a chronic disabling condition, which occurs frequently in our society, requiring a major investment of medical care.

Age Factors↗
PubMed1990

[Basic principles of compression therapy].

The empirically established positive effects of the compression in the syndrome of the chronic insufficiency of the veins are widely accepted. Nevertheless the theoretical interpretation of these effects is often difficult, and even, depending on the criterion chosen, contradictory results can be yielded, particularly with regard to the influence on the pumping function of the veins. The experiences concerning these compression effects are reported, taking into consideration the non-linear relation between venous pressure and volume of the extremities and paradoxical results are explained.

Bandages↗
PubMed1985

[Skin blood flow measurement in microangiopathic changes].

The classical Martorell-ulcer, which is--according to the original criteria--rather rare, is preceded and accompanied by characteristic microangiopathic signs, the so-called "Pigmented Praetibial Patches" (PPP's). These signs are of great diagnostic significance. In complicated pathology it is important to measure skin blood flow and especially the reactions on a temporary arterial occlusion and on the application of a vasodilating ointment. For this purpose a method is used, based upon measurement of heat transport in the superficial 1.5 mm of the skin.

Humans↗