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Biomedical subjects

J P Kelley

Publications and source records attributed to J P Kelley.

At least 19 recordsLinked to original sources
PubMed1984

The fate of severed corticospinal axons.

The potential for regeneration of severed corticospinal axons was examined by labeling these axons with horseradish peroxidase following thoracic spinal cord transections in mice. Shortly after severance, the proximal ends of corticospinal axons formed terminal bulbs that persisted for weeks and were associated with axonal retraction. There were few signs of corticospinal axonal sprouting or elongation. By 2 months after injury, corticospinal axons near the transection site showed an increased number of probable labeled terminals in the adjacent gray matter. These new terminals may contribute to the persistence of many corticospinal axons near the injury site long after a spinal cord transection.

Animals↗
PubMed1975

Sequence of electromyographic abnormalities in stroke syndrome.

In 20 stroke patients who were examined by repeated electromyography, fibrillation potentials and positive waves were noted as early as seven to ten days after the stroke and gradually disappeared as volitional potentials and spasticity appeared. This sequence of events occurred first in the antigravity muscles, then in their antagonists and finally in the most distal muscles. We hypothesize that the abnormal irritability is a consequence of the loss of the neurotrophic influence on the muscle fiber after the stroke.

Adult↗