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Biomedical subjects

J P Bethoux

Publications and source records attributed to J P Bethoux.

29 records · Page 2Linked to original sources
PubMed1990

[Implantation of pancreatic islets in arteriolar epiploic flap. Preliminary note on 3 cases].

Presently, no long-term insulin withdrawal after islet graft in a diabetic patient has been reported. From October 1988 to December 1989 we have performed 3 pancreatic islet grafts in 3 type I diabetic patients. Islets were isolated from pancreatic glands collected during multiple organs harvesting. Implantation was conducted in an original site, by an arteriolar embolization of an epiploic flap pedicled from the right gastroepiploic vessels. Those grafts were combined twice with a kidney and in one occasion with a liver transplant. After 15 months, this last case is an unique metabolic success with complete insulino-independence. Endogenous insulin-secretion determined by C-peptide measurement was not detectable before surgery but was normalized and stimulable 6 months after the graft. Insulin injections were stopped one month later. Blood glucose is fully normal since 8 months without insulin. For the two other cases with kidney transplants after two months, endogenous insulin is already detectable. Compared with 3 segmental pancreatic grafts performed during the same period, islet graft in diabetic patients appears as a promising approach.

Adult↗
PubMed1989

Computed tomography of retained abdominal sponges and towels.

The diagnosis of retained sponges and towels a year or more after surgery is often very difficult. We describe the computed tomographic (CT) findings in 4 patients with this complication; 2 cases of retained sponges and 2 cases of retained towels. While the CT appearance of the retained sponges was not specific, the particular appearance of the retained towels had not been previously described. This appearance is characteristic enough to suggest the correct diagnosis before reoperation.

Abdomen↗
PubMed1985

[Rectocolic endometriosis].

The authors distinguish two major varieties of rectocolonic endometriosis: the isolated benign sigmoid endometrioma which is difficult to distinguish from malignant lesions of the mucosa; the tendency to progressive stenosis is an indication for surgical excision of this lesion. Genital endometriosis which has spread to the intestinal tract. The genital and peritoneal lesions facilitate the diagnosis of the recto-sigmoid lesion. On the other hand, the intestinal involvement complicates the therapeutic. Low rectal involvement usually consists of endometriosis grafted to a perineal scar.

Endometriosis↗
PubMed1977

[Turner's syndrome phenotype and spontaneous menstruation. Apropos of a case of 45 X syndrome].

The authors report a new case where a women of 28 years of age started periods spontaneously in spite of having the phenotype of Turner's syndrome and a 45 X karyotype in her lymphocytes and fibroblasts. When she had been stimulated with Clomiphene it was even possible to prove that she had ovulated and produced a functional corpus luteum. No Barr bodies were to be found in the cells from her ovaries and the karotype did not suggest a mosaic which would normally explain this sort of state. All the same, it is difficult to see how any part of the basic follicles can persist in cases of monosomy 45 X if there is no mosaicism.

Adult↗