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Biomedical subjects

J Ovesen

Publications and source records attributed to J Ovesen.

At least 55 records · Page 3Linked to original sources
PubMed1984

Rotatory instability of cadaver knees after transection of collateral ligaments and capsule.

The importance of the medial and lateral compartment ligaments of the knee in relation to valgus-varus and axial rotation instability was investigated. Mobility patterns were drawn from 20 osteoligamentous knee preparations after successive transections of the structures. Cutting of the medial collateral ligament resulted only in slight valgus instability and modest anteromedial instability. When the medial posterior joint capsule was also cut, both types of instability increased, and moreover, the knee became posteromedially unstable. Cutting of the lateral collateral ligament produced only a little varus instability and anterolateral rotatory instability, but varus instability increased considerably when the posterior lateral capsule was also transected. In this latter situation, even marked posterolateral rotatory instability was found. Isolated transection of the medial or lateral collateral ligament did not cause any major valgus or varus instability, but when the posterior capsule was also transected, a considerable degree rotatory instability could be found even though the cruciate ligaments were intact.

Biomechanical Phenomena↗
PubMed1984

The anterior cruciate ligament of the knee: an experimental study of its importance in rotatory knee instability.

The importance of the anterior cruciate ligament (ACL) in relation to valgus-varus and axial rotation stability in the knee joint was investigated. Mobility patterns were drawn from ten osteoligamentous preparations after successive transection of the two parts of the ACL and the medial (MCL) and lateral collateral ligaments (LCL). The knee joint remained grossly stable after partial injury of the ACL, while sectioning of the entire ACL caused an increase in internal rotation in the extended-semiflexed position. Combined lesions to the ACL and the MCL caused considerable valgus instability increasing with flexion, the joints remaining stable in extension. Moreover, marked anteromedial instability occurred, while only slight posteromedial instability was found. Combined lesions to the ACL and the LCL caused varus instability, worst in the semiflexed position, and a consistent pivot shift in applying a valgus torque in flexion was noted. Moreover, moderate posterolateral instability was found, at its maximum in the semiflexed position. External rotatory stability is secured primarily by the MCL, secondarily by the posterior medial capsule, and finally by the ACL. The existence of lateral pivot shift is proof of damage to the ACL.

Humans↗
PubMed1984

Nicholson score for prescribing digoxin compared with Jellife nomogram.

A series of 84 medical inpatients were treated in random order with oral digoxin in doses calculated according to the newly introduced Nicholson score and the Jellife formula and nomogram. The daily dose of digoxin was lower (p less than 0.01) according to the Nicholson score (mean 2.1 digoxin tablets of 62.5 micrograms daily). The mean serum concentration of digoxin was also lower (p less than 0.01) according to the Nicholson score (1.27 nmol/l) than according to the Jellife nomogram (1.84 nmol/l). Estimated by the Nicholson score the serum concentration of digoxin was not optimal (p less than 0.01) and not within an acceptable therapeutic range (p less than 0.01) in more patients than when estimated by the Jellife nomogram. It is concluded that the Nicholson score is not suitable for medical inpatients.

Aged↗
PubMed1984

Measurement of skin perfusion pressure by photoelectric technique--an aid to amputation level selection in arteriosclerotic disease.

During a period of 14 months 60 amputations, 41 below-knee and 19 above-knee, were performed on 54 patients with gangrene of the lower limb. Wound healing was evaluated in 59 amputations. A newly introduced standardized photoelectric technique for measurement of the local skin perfusion pressure (SPP) was used preoperatively, the result of which served as a guide to the selection of the proper amputation level. An overall healing rate of 90 per cent was found. Sixty-eight per cent of the amputations were performed below-knee. The healing rates for individual SPP levels were identical to those obtained with the isotope washout technique. The standardized photoelectric technique is simple and rapid and gives only negligible discomfort to the patient allowing repeated measurements at different levels on the leg.

Adult↗
PubMed1983

The day-to-day variation in serum digoxin concentration. The Hørsholm digoxin study.

Serum digoxin concentration was measured in 70 medical patients 7 and 8 days after admission to hospital. The digoxin treatment taken at home was continued in hospital. There was no statistically significant difference between mean digoxin concentrations in samples taken at day 7 (1.52 nmol/l) and day 8 (1.48 nmol/l). The variation in serum digoxin concentration from day to day expressed as SD was 0.25 nmol/l; 95% confidence limits were +/- 0.51 nmol/l, and 99% confidence limits +/- 0.67 nmol/l. Variations in serum digoxin concentration were not correlated to age, sex, body weight, serum creatinine and the oral dose of digoxin.

Aged↗
PubMed1982

Standardized photoelectric technique as routine method for selection of amputation level.

During a period of 11 months 45 amputations, 31 below-knee and 14 above-knee, were performed in 42 patients with gangrene of the lower extremity. A newly introduced standardized photoelectric technique for measurement of local skin perfusion pressure (SPP) was used preoperatively and the result used in selection of the proper amputation level. An overall healing rate of 89 per cent was found. 69 per cent of the amputations were performed below-knee. The healing rates for individual SPP-levels were identical to those obtained with the cumbersome isotope washout technique. The standardized photoelectric technique is simple, rapid and causes the patient only negligible discomfort, allowing repeated measurements on different levels of the leg.

Adult↗