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Biomedical subjects

J Oliver

Publications and source records attributed to J Oliver.

At least 181 records · Page 10Linked to original sources
PubMed1983

Gonadotropic and photosensitive abilities of the lobus paraolfactorius: electrophysiological study in quail.

Spontaneous and flash-altered multiunit activity MUA was recorded from the lobus paraolfactorius of young male quail reared in either long or short daily photoperiods. The birds were subjected to testosterone administration, castration, optic nerve section or retroparaolfactory disconnection and compared to intact controls. In all experimental and intact quail, iterative flashes led to decreased paraolfactory MUA. Spontaneous firing rates were found to be significantly higher during the light than during the dark part of the photoperiods, indicating some direct effect of environmental lighting on the paraolfactory neuronal populations. However, blinded as well as paraolfactory disconnected animals failed to exhibit any difference in firing rates according to the daily short and long photoperiods as seen in controls, suggesting that the light regime might also indirectly influence the paraolfactory activity.

Animals↗
PubMed1982

House dust mites in Bristol.

A survey of bedding in Bristol revealed reducing mite concentrations on children's toys, mattresses, overblankets and pillows. Dermatophagoides pteronyssinus was the commonest mite found. A vacuuming schedule was devised for removing mites so that a double blind trial could be carried out. Investigation suggests that even with expert utilization of efficient vacuum cleaners the clinical efficacy would be limited as the mites appear to rapidly migrate back into the bedding.

Allergens↗
PubMed1981

Discrete distributions of putative cholinergic and somatostatinergic amacrine cell dendrites in chicken retina.

The distributions of putative cholinergic and somatostatinergic amacrine cells of the chicken retina were compared. Acetylcholinesterase-positive amacrine cell bodies were concentrated at the border between the inner nuclear and plexiform layers. Similar amacrine cell bodies were detected in a displaced position in the ganglion cell layer. Both populations had dendrites joining the 4 bands of acetylcholinesterase activity in the inner plexiform layer. The cell bodies of somatostatin-immunoreactive amacrine cells were distinct from the intensely acetylcholinesterase-positive cell bodies. The immunoreactive terminal bands did not overlap the acetylcholinesterase-positive bands, except in the inner parts of the inner plexiform layer.

Acetylcholinesterase↗
PubMed1981

Translocatable resistance to mercuric and phenylmercuric ions in soil bacteria.

Of a sample of 42 gram-negative Hg-resistant bacteria, three (a Pseudomonas fluorescens, a Klebsiella sp. and a Citrobacter sp.) contained translocatable elements conferring resistance to Hg2+ (all three) and to Hg2+ and phenylmercuric acetate (P. fluorescens). The discovery of transposable phenylmercuric acetate resistance extends the range of known resistance "transposons" from heavy metals and antibiotics to organometallic compounds.

Bacteria↗
PubMed1980

Implementation of adjuvant therapy for breast cancer in the St. Louis Metropolitan area: 1976-1977.

In order to determine the extent of implementation of adjuvant chemotherapy for stage II carcinoma of the breast in the St. Louis area, records of all patients with stage II carcinoma of the breast treated with standard or modified radical mastectomy in five different St. Louis hospitals were reviewed. Between July 1, 1976, and July 1, 1977 (17 months after publication of preliminary L-PAM results and 4 months after publication of preliminary L-PAM results and 4 months after publication of preliminary CMF results), 73% of 24 premenopausal patients and 55% of 58 postmenopausal patients received adjuvant chemotherapy. Ten percent of premenopausal and 31% of postmenopausal patients received therapy other than CMF or L-PAM. Compared to premenopausal patients in university-affiliated hospitals, premenopausal patients in community hospitals tended to receive radiation therapy more commonly and chemotherapy alone less often (P < 0.1). Compared to postmenopausal patients in university-affiliated hospitals, postmenopausal patients in community hospitals more commonly received chemotherapy alone, and less often received no adjuvant therapy (P < 0.05). We conclude that results of adjuvant chemotherapy trials can be rapidly implemented into standard practice both in university-affiliated and community hospitals. Since 12 of 52 patients receiving adjuvant chemotherapy in fact received nonstandard, unpublished regimens, improvements in phase IV drug development may be required to prevent potentially deleterious modifications of published recommendations.

Adult↗