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Biomedical subjects

J O'Rourke

Publications and source records attributed to J O'Rourke.

105 records · Page 6Linked to original sources
PubMedDate not supplied

Optimized graphical analysis of Gaussian and lognormal assumptions for intraocular and vascular pressure distributions.

The design of optimized histogram and probability graphs needed to detect a lognormal distribution in surveys of intraocular pressure (IOP), mean ophthalmic arterial pressure (OAP) and mean ocular perfusion pressure (OPP) is described. Applications are demonstrated in a sample of 58 normal adult eyes. A lognormal distribution was found for IOP and for OAP and OPP estimates obtained with a noncontact noncompressive method. Conversely, the absence of an identifiable linear distribution for OAP and OPP estimates obtained with compression ophthalmodynamometry was noteworthy. The implications of lognormality for definitions of a normal range and for correlations involving IOP, OAP and OPP data are briefly discussed.

Adult↗
PubMedDate not supplied

Application of a minicomputer-based system in measuring intraocular fluid dynamics.

A complete, computerized system has been developed to automate and display radionuclide clearance studies in an ophthalmology clinical laboratory. The system is based on a PDP-8E computer with a 16-k core memory and includes a dual-drive Decassette system and an interactive display terminal. The software controls the acquisition of data from an NIM scaler, times the procedures, and analyzes and simultaneously displays logarithmically converted data on a fully annotated graph. Animal studies and clinical experiments are presented to illustrate the nature of these displays and the results obtained using this automated eye physiometer.

Animals↗