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Biomedical subjects

J O Tobin

Publications and source records attributed to J O Tobin.

44 records · Page 3Linked to original sources
PubMed1970

Isolation of rubella virus from abortion material.

Rubella virus was isolated from the fetus or products of conception in 29 out of 32 cases (91%) terminated because of clinical maternal rubella proved or supported by laboratory findings in the first trimester of pregnancy. Virus was isolated from similar material from only 3 out of 19 (16%) other clinical cases of rubella in which the laboratory findings were inconclusive or against the diagnosis or in which no laboratory tests were done. Virus was found in the amniotic fluid if the fetus was infected and there was no evidence that the placenta was any real barrier to fetal infection.

Abortion, Therapeutic↗
PubMedDate not supplied

Rubella in the United Kingdom, 1970-1983.

The numbers of acquired and congenital rubella infections in the United Kingdom were obtained from clinical and laboratory reports and from notifications to the National Congenital Rubella Surveillance Programme. Since 1970 the annual frequency of clinical infection has varied from 150 to 450 cases per 100,000 population and laboratory reports of infection, from 800 to 4,100 per year. The number of notified congenital rubella infections varied from 12 to 86 per year. The largest recent epidemics occurred in 1978 and 1979, with an increase in the number of congenital rubella infections during the following winters. Increased numbers of cases occurred every one to three years, with troughs of two to three years, but peaks in different localities often did not coincide. Terminations of pregnancy associated with rubella or rubella vaccination during pregnancy are reported by the Office of Population Censuses and Surveys and vary with the incidence of acquired rubella; a maximum of 830 abortions were performed in 1978 for women who acquired the disease, and from 27 to 156 were performed each year for women vaccinated just before or soon after becoming pregnant. The effect of the vaccination program is discussed in relation to the decrease in the number of young women without rubella antibody.

Abortion, Induced↗