Biomedical subjects

J O Sipperley

Publications and source records attributed to J O Sipperley.

22 records · Page 2Linked to original sources

PubMed1981

Histopathologic evaluation of adhesive properties of early lesions in diathermy and cryopexy.

We examined the histopathologic appearance of both cryopexy and diathermy lesions, 10-60 min after application in the rabbit retina. Both lesions showed immediate subretinal exudation. Thus, we could not substantiate the speculation that a diathermy lesion might have greater immediate adhesive strength than a cryotherapy lesion. This explains the clinical experience that retina tends to slip with either modality when trying to treat giant retinal tears.

Adhesiveness↗

PubMed1978

Small melanomas of the choroid.

We reviewed 38 cases of small choroidal melanomas on file in the Eye Pathology Laboratory of Bascom Palmer Eye Institute, Miami. Clinical and histopathological features of these cases were noted, and clinical follow-up information was obtained for 36 (95%) of the patients. Two tumor deaths occurred among the 18 patients that had a possible follow-up period of six years of more, yielding a tumor death rate of 11%. Retrospective analysis of clinical records and photographs permitted us to correlate the presence or absence of documented tumor growth with the degree of mitotic activity.

Adolescent↗

PubMed1978

Traumatic retinopathy in primates. The explanation of commotio retinae.

We have produced experimental commotio retinae in 12 owl monkeys by blunt trauma. The ophthalmoscopic and fluorescein angiographic appearance of this contrecoup lesion is identical to the acute traumatic retinal opacity in humans. We examined these eyes by light and electron microscopy from 4 hours to 12 weeks after injury. Immediately after injury, the only abnormality is disruption of the receptor outer segments. From one to six days after trauma, many receptor cells undergo degeneration. The retinal pigment epithelium phagocytoses the degenerating outer segments, occasionally migrating into the retina. There is no extracellular retinal edema. The opacity of commotio retinae seems to represent disrupted receptor cells. Visual loss may result from permanent loss of receptors. The pigment epithelial response to traumatic receptor damage is similar to that observed in experimental retinal detachment and light-induced retinal damage.

Animals↗

PubMedDate not supplied

Autosomal dominant preretinal vascular loops.

Preretinal vascular loops are a congenital malformation usually occurring in otherwise normal fundi. These anomalies consist of vessels, most commonly arteries, that spiral into the vitreous and return to the otherwise normal retinal vascular system. The authors present two members of a family with preretinal vascular loops and two members with other vascular anomalies. The inheritance pattern in this group is autosomal dominant.

Adult↗