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Biomedical subjects

J O Holm

Publications and source records attributed to J O Holm.

12 recordsLinked to original sources
PubMed1995

[Contact allergy to essential oils].

Ethereal oils are widely used, in food, toothpaste, as flavouring agents in perfumes and cosmetics, and in dermatological treatment, as antiseptics, adstringenta, antipruritic tinctures, lotions and pomades. The use of ethereal oils seems to have increased in recent years, probably due to a growing interest in alternative medicine, and especially aromatherapy. By describing the cases of three patients with allergic contact dermatitis, we wish to point out possible unwanted side effects of using ethereal oils.

Adult↗
PubMed1994

[Atopic eczema].

Atopic eczema is one of the most common skin diseases of our time, and has commonly been regarded, without further proof, as caused by allergic factors. Although allergy may be involved in some cases, it is probably no more than an exacerbating factor and not the underlying cause. This has important implications for diagnosis and therapy. In recent years the interest has centred on the functional aspects of the skin barrier, with emphasis on lipid constituents in stratum corneum. The authors present some new data on the barrier function which are relevant to diagnosis and therapy.

Dermatitis, Atopic↗
PubMed1994

[ADP-registration of patients with contact dermatitis at the Ullevål hospital. A 1-year material].

Databases for monitoring patients with contact dermatitis have become indispensable for managing a constantly increasing variety of products which cause allergic and toxic dermatitis. As a result of collaboration between the Department of Dermatology and Department of Information Technology, Ullevål Hospital, we now have developed a database for registering patients with occupational dermatitis. The programming tool is DataEase, which contains files for the patients' personal data, site of the dermatitis, results of tests and diagnosis.

Adolescent↗
PubMed1993

[Epicutaneous testing (patch testing)].

At present, patch testing is the only practical way of diagnosing allergic contact dermatitis, manifested as delayed hypersensitivity (type IV reaction). It can serve to confirm relevant allergens, but may also help to exclude suspected contact sensitivity. The test procedure varies somewhat from one clinic to another but has been standardized by the International Contact Dermatitis Research Group. Choice of test materials and their application may appear simple, but test readings and interpretation of results are most important. Positive reactions can be positive (allergic) or false positive (irritant), and relevant or not relevant to an existing or previous dermatitis. The dermatologist is the person best qualified to diagnose contact dermatitis by this test procedure.

Dermatitis, Allergic Contact↗
PubMed1993

[Rubber allergy. An increasing health problem?].

Allergic reactions to rubber (latex) are now being reported more frequently. Symptoms include urticaria, contact dermatitis, rhinitis, local angioedema, asthma and anaphylactic shock. Medical workers and some groups of patients seem to be at risk of developing rubber allergy. The increased use of rubber gloves and condoms to prevent the spread of infections seems to lead to increased incidence of latex hypersensitivity. We report the case of a patient who experienced an immediate allergic reaction after using a condom. We then discuss latex antigens, the incidence and diagnosis of latex allergy, and associated risk factors.

Adult↗
PubMed1993

[Delayed allergy against rubber gloves. An occupational dermatitis among health personnel].

Allergic reactions to rubber gloves, an increasing problem in medical health services, have become an prominent topic in occupational dermatology. A broad spectrum of immunological mechanisms are involved, from antibody-induced immediate reactions to delayed cell-mediated reactions. We review the causes of the reactions and discuss diagnostic procedures. The main allergens are rubber additives, such as accelerators and antioxidants. In this connection it is important to develop and produce gloves using other basic materials and ingredients, and thereby avoid the most frequent allergens.

Dermatitis, Occupational↗