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Biomedical subjects

J Nowicki

Publications and source records attributed to J Nowicki.

69 records · Page 4Linked to original sources

The value of distal greater trochanteric transfer in the treatment of deformity of the proximal femur owing to avascular necrosis.

A series of 49 patients (55 hips) who had distal greater trochanteric transfer at the mean age of 13.9 years because of the deformity of the proximal femur after treatment for developmental dislocation of the hip was reviewed to verify the value of the procedure. Mean follow-up was 8.8 years. Clinical and radiologic assessment was supplemented with strain-gauging evaluation of the muscles involved. Good results were achieved in patients who had good range of movement or isolated restriction of abduction before the operation. After surgery, a 22% increase of abductors torque was found, the Trendelenburg sign disappeared in 30 individuals, and 15 patients regained normal gait. No complications were observed. Our study confirmed the value of distal transfer of the greater trochanter in treatment for proximal femur deformity owing to avascular necrosis after management of developmental dislocation of the hip and clarified indications for this procedure.

Adolescent↗

[Venous blood concentration of pyruvates in patients with stroke].

The concentration of pyruvate in the venous blood of 31 patients with stroke was determined by the enzymatic spectrophotometric method. The pyruvate concentration was raised on the 1st, 3rd and 10th days after stroke and this increase was statistically significant. Pyruvate concentration changes in venous blood were associated with severe clinical condition of the patients.

Adult↗

[Effect of hydantoins on urinary excretion of 5-hydroxyindoleacetic acid].

The investigations were carried out in 10 patients with epileptic seizures. The obtained results were compared with those in a control group of 20 healthy subjects. The 24-hour urinary excretion of 5-HIAA efore hydantoinal and on the 1st, 2dn and 3rd days of hydantoinal administration was determined by the method of Udenfried et al. as modified by McFarlane et al. It was found that healthy subjects excreted significantly more 5-HIAA before and after hydantoinal load. Administration of this drug increased significantly the excretion of this metabolite with urine, in healthy subjects but in epileptics it had no significant effect on 5-HIAA level in 24-hour urine.

Adolescent↗

[Bronchial injury].

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Adolescent↗

[Glucose, pyruvate and lactate concentrations in the cerebrospinal fluid in patients with cerebral infarction].

The determinations were performed in cerebrospinal fluid of 50 patients with recent cerebral infarction in the 1-st, 3-rd and 10-th day of disease. Spectrophotometrie methods were used for the determination of lactate and pyruvate and a colorimetric method for glucose determination. A statistically significant increase of glucose in the cerebrospinal fluid on the 1-st day after cerebral infarction and of pyruvate, lactate and lactate: pyruvate index on 1-st and 3-rd day after cerebral infarction was found. The results obtained point to intensification of the anaerobic pathway of glucose metabolism.

Adult↗