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Biomedical subjects

J Nordling

Publications and source records attributed to J Nordling.

149 records · Page 9Linked to original sources

Alpha-blockers and urethral pressure in neurological patients.

In 11 patients with upper motor neuron bladder paresis due to spinal trauma, 2 patients with lower motor neuron bladder paresis, and 4 patients with multiple sclerosis, alpha-adrenergic blockade with 10 mg Regitine intravenously decreased the maximum urethral closure pressure to an average of 42%. The decrease was most pronounced in a patient with lower motor neuron bladder paresis and a flaccid pelvic floor. Treatment with phenoxybenzamine was found valuable in patients with multiple sclerosis and poor bladder emptying as well as in patients with lower motor neuron bladder paresis. In patients with detrusorsphincter dyssynergia this treatment was of no value.

Adrenergic alpha-Antagonists↗

Human sympathetic bladder innervation. A morphological investigation.

A method for histochemical determination of noradrenergic nerve fibers in human bladder biopsies is described. The importance of an objective criterium for distinguishing between specific noradrenaline fluorescence and autofluorescence of connective tissue is stressed. In 2 females and 3 males without neurogenic bladder disease the noradrenergic innervation of the detrusor as well as the trigonal muscle was found very scarce.

Animals↗

Repeated, rapid fill CO2-cystometry.

114 consecutive patients were subjected to double, rapid fill CO2-cystometry. In 106 the two cystometries were of the same type, although several cystometric values changed statistically significantly. In eight patients the two cystometrograms were of a different type with uninhibited detrusor contraction in one but not in the other. A possible explanation for this is discussed.

Carbon Dioxide↗