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Biomedical subjects

J Noone

Publications and source records attributed to J Noone.

At least 19 recordsLinked to original sources

Cultural perspectives on contraception: a literature review.

The incorporation of transcultural nursing concepts has become an integral component of holistic nursing practice. However, to deliver culturally appropriate nursing care, knowledge of cross-cultural health beliefs and practices is necessary. This article reviews cultural perspectives on contraception based on a literature review of qualitative and quantitative health care research studies related to the topics of culture and contraception. The purpose of this literature review is to provide a knowledge foundation for health care providers who provide contraceptive counseling. Implications for practice, as well as recommendations for future research, are developed.

Black or African American↗

Information overload: opportunities and challenges for the GP's desktop.

Recent developments in health data networks, the health sector and information systems, have created an overload of information available to the General Practitioner. The implementation of viable Health Data Networks within hospitals and subsequent connection to the GP's desktop PC enables increased access to patient records, decision-support and communication with experts around the world To address the high usage of expensive health services and lengthy waiting lists health services around the world are embracing programs such as Community, Coordinated, Shared and Managed care. This focus on coordination of care and increased emphasis on evidenced-based medicine is greatly enhanced through the advent of viable health data networks. Other resources such as databases, best-practice guidelines, the web, email, telemedicine and a range of commercial programs that provide further services has created an overload of resources available to the GP. Current human-computer interface guidelines are not adequate for prescribing design solutions to deal with the information overload facing GPs. The challenge for the near future is to present the vast array of information sources to the GP in an acceptable and useable information system interface. Part of the solution may revolve around the development of standards for Electronic Health Record systems for GPs, as is being done currently in Australia; but we suspect that less mainstream interface technologies will be required to exploit the wealth of available healthcare information.

Australia↗

Bell's palsy in the primary care setting: a case study.

Bell's palsy is an acute unilateral paralysis of the facial muscles innervated by the seventh cranial nerve. Although the etiology of Bell's palsy is unknown, it is thought to result from edema, entrapment, or inflammation of the seventh cranial nerve. A history of recent viral infection--especially herpes simplex--diabetes mellitus, pregnancy, or hypertension are all common risk factors that may precede the onset. This article reviews assessment findings, differential diagnoses, and the treatment of Bell's palsy, which is considered a diagnosis of exclusion. A 10-day course of oral corticosteroids is the recommended therapy for lessening its course and severity in some populations. Recent research recommends the addition of acyclovir for 10 days, suggesting a herpetic viral etiology. Close follow-up is imperative to prevent corneal injury and to monitor worsening of symptoms. Although most patients recover within 1 to 6 months, incomplete recovery may be seen in severe or recurrent cases. Indications for referral are discussed. A case study is presented to illustrate the findings in this interesting disease.

Acyclovir↗

Diagnosis and treatment of leptospirosis in the primary care setting.

Leptospirosis is an infectious illness that usually develops 1 to 2 weeks after indirect or direct exposure to the urine of infected animals. Infection occurs through open cuts, absorption through intact mucous membranes, and drinking contaminated water. The typical presentation is a flulike syndrome of sudden onset that tends to resolve within 2 weeks. A mild immunologic phase usually presents as an aseptic meningitis. A more severe immunologic phase (Well's syndrome) can result in jaundice, renal failure, adult respiratory distress syndrome, disseminated intravascular coagulation, and death. Laboratory tests take too long to replace clinical diagnosis, which is imperative so that antibiotic therapy can begin before the fourth day of illness. Although leptospirosis is more common in tropical climates, detection in the continental United States is increasing. Early, accurate detection and treatment in the primary care setting are vital for limiting life-threatening complications.

Diagnosis, Differential↗

Mechanisms of arrhythmias: enhanced automaticity and reentry.

Table 2 provides an overview of the classifications of antiarrhythmic agents, their actions, and their uses against reentrant arrhythmias and those caused by enhanced automaticity. Table 3 reviews many of the differences between the two mechanisms of arrhythmias: enhanced automaticity and reentry. Clinical distinction will assist in the most appropriate choice of therapy for terminating cardiac arrhythmias.

Anti-Arrhythmia Agents↗

Interaction between cortisol and microbial proteases.

Binding (or interaction) of cortisol with microbial molecule(s) was observed by employing Bio-Gel HTP affinity chromatography and subsequently by fluorescence spectrophotometry. Molecule(s) in the crude extract of baker's yeast and in other microbial proteases exhibited varied degrees of cortisol-binding. Bacterial protease (type IX) had highest, while the type XXVI enzyme had the lowest, binding capacity. In addition, these two proteases exhibited a distinct difference in the alterations of ultraviolet spectra due to interaction with cortisol. Using casein as a substrate, cortisol, CTP, trypsin inhibitor or leupeptin appreciably inhibited type IX protease at low concentrations of Ca2+. However, thyroxine had no effect on this protease.

Bacteria↗