[Sexual activity in men with Klinefelter's syndrome].
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Biomedical subjects
Publications and source records attributed to J Neuwirth.
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The values of serum T4, T3, T4/T3, RT3U, FT4I, PBI, ATR, TSH, 132I uptake and antibodies against thyreoglobulin were estimated in non-obese, healthy women and in obese women with a stabile body weight on total fasting of 14 days. Obesity with no dietary restriction compared with normal controls was accompanied by a tendency to higher serum levels of T4 and T3 and prolonged ATR. Other indicators of thyroid function remained unchanged. Total fasting led to a decrease of serum T3 and to an increase of FT4I and RT3U. The remaining tests were unchanged. These results are conform with a decreased transformation of T4 into T3 in the periphery. The participation of the hypothalamus and hypophysis to adaptation of the thyroid to fasting was discussed.
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Clinical, spermiologic and karyologic examinations and determinations of plasmatic testosterone were performed in a group of 105 chromatin-positive patients aged 16 to 45 years. A comparison with a control group of 108 somatosexually well developed and fertile men at the age of 21 to 55 years has established that in the Klinefelter's syndrome the male sex hormone level in the blood was highly significantly lower. Whereas in the control group the male sex hormone values in the blood were dependent on age, it was not possible to prove any dynamic changes in the process of ageing between 21 and 45 years in chromatin-positive patients. A comparison of some phenotypical and laboratory findings in the various chromosomal variants of Klinefelter's syndrome shows that comparatively the least changes were found in patients with a mosaic of 46,XY/47,XXY.
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