Biomedical subjects

J Neill

Publications and source records attributed to J Neill.

28 records · Page 2Linked to original sources

PubMed1980

Disruption in the temporal sequence of regional ventricular contraction. I. Characteristics and incidence in coronary artery disease.

While spatial asynergy at end-systole has been well characterized in patients with coronary artery disease, assessment of regional asynchrony has been hampered by technical constraints. We developed a computer-assisted method for analyzing regional asynchrony from the equilibrium (ECG-gated) radionuclide ventriculogram. Twenty patients with normal contrast left ventriculograms (nine with a normal coronary arteriogram [group 1] and 11 with coronary artery disease [group 2]) and 20 patients with asynergy during contrast ventriculography (group 3) were studied. The earliest evidence of regional asynchrony occurred in early systole. Regional ejection fraction at one-third systole was 0.32 +/- 0.02 (mean +/- SEM) in group 1, 0.22 +/- 0.01 in group 2 (p less than 0.001) and 0.12 +/- 0.01 in asynergic regions in group 3 patients (p less than 0.001). In group 3, severe forms of regional asynchrony appeared in both early systole and early diastole: five patients (25%) had early systolic paradox, 13 (65%) had regional prolongation of peak ejection fraction and 16 (80%) had reduced percent peak ejection fraction at global end-systole. It appears, therefore, that there is progressively increasing regional asynchrony in patients with increasing severity of coronary artery disease.

Coronary Angiography↗

PubMed1979

The paradox image: a noninvasive index of regional left-ventricular dyskinesis.

The paradox image, a functional image of regional dyskinesis derived from the equilibrium (gated) radionuclide ventriculogram, was constructed by subtracting the background-corrected end-diastolic frame from the background-corrected end-systolic frame. In 11 patients showing dyskinesis by contract ventriculography, the percentage of left-ventricular picture elements containing paradox ranged from 3.6 to 55.6% (21.44% +/- 4.45 s.e.m.). In 11 patients with normokinesis and in eight patients with hypokinesis by contract ventriculography, the left-ventricular picture elements demonstrating paradox were less than 1.1% in all cases. In nine patients with akinesis, the percentage of left-ventricular picture elements containing paradox was 2.05% +/- 0.96 s.e.m. and was less tha 2% in seven patients. There was also an excellent agreement between the location of dyskinesis on the paradox image and that by contrast ventriculography. The paradox image is a sensitive indicator of left-ventricular dyskinesis and should be useful in the evaluation of patients with suspected left-ventricular asynergy.

Cardiac Output↗

PubMed1977

The removal of a psychosomatic symptom: effects on the marriage.

This study examined the effects on the marriages of twelve patients who underwent intestinal bypass surgery for extreme obesity. Marked conflict and disruption were observed. Most striking were changes in the areas of sexuality and dependence/independence parameters. The authors discuss the function of the symptom of obesity within these marital systems.

Anxiety, Separation↗

PubMed1972