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Biomedical subjects

J Naylor

Publications and source records attributed to J Naylor.

22 records · Page 2Linked to original sources
PubMed1976

Prevalence of malnutrition in general medical patients.

Three, single-day nutritional surveys at weekly intervals were conducted in the general medical wards of an urban municipal teaching hospital. The techniques of nutritional assessment included anthropometric measures (weight/height, triceps skin fold, arm-muscle circumference, serum albumin, and hematocrit). The prevalence of protein-calorie malnutrition was 44% or greater by these criteria (weight/height, 45%; triceps skin fold, 76%; arm-muscle circumference, 55%; serum albumin, 44%; and hematocrit, 48%). These results were reproducible without significant variation between surveys. In 34% of patients, a lymphopenia of 1,200 cells/cu mm or less was found, a level likely to be associated with diminished cell-mediated immunity. Compared with a similar survey among surgical patients, the medical patients were more depleted calorically (weight/height, triceps skin fold) but had better protein status (arm-muscle circumference, serum albumin). Significant protein-calorie malnutrition occurs commonly in municipal hospitals in both medical and surgical services.

Adult↗
PubMed1972

Isolation of protective somatic antigen from Vibrio cholerae (Ogawa) ribosomal preparations.

Ribosomal preparations from Vibrio cholerae Ogawa and Inaba are protective immunogens for mice challenged with either serotype. Column chromatography of ribosomal fractions separated protective antigen from the ribosomes. The antigen is a heterogeneous colloid which contains protein, lipid, and carbohydrate in the ratio 3:1:1. Amino acid composition is that of a slightly acidic protein with no unusual complement of amino acids. The lipid component consists of several longchain fatty acids and of phosphatidyl ethanolamine. The major sugars identified were glucose and galactose. The colloid can be dissolved by treatment with chelating agents and sodium dodecyl sulfate. Purification of the solubilized material or of the colloid was unsuccessful.

Amino Acids↗
PubMedDate not supplied

Determination of mycotoxins in pet foods sold for domestic pets and wild birds using linked-column immunoassay clean-up and HPLC.

A technique referred to as 'linked-column immunoassay clean-up', was developed for the simultaneous determination of aflatoxins and ochratoxin A in a range of dry cereal-based pet foods and wild bird food. In addition a method also based on clean-up using immunoaffinity columns was used for the determination of fumonisin mycotoxins in samples known or suspected to contain maize. One hundred samples of pet foods consisting of 35 samples of domestic bird seeds and 15 samples of wild bird food were examined for aflatoxins B1, B2, G1 and G2 and ochratoxin A. Twenty samples of these samples were also examined for fumonisins B1 and B2. Limits of detection were about 0.5 micrograms/kg for each aflatoxin and ochratoxin A and 3 and 8 micrograms/kg for fumonisins B1 and B2 respectively. Eighty-four percent of the samples contained no measurable concentrations of mycotoxins. A low level of aflatoxin B1 was found in a sample of cat food and a concentration of 370 micrograms/kg aflatoxin B1 in one sample of peanuts marketed for wild birds. Ochratoxin A was detected in 10% of samples but in low concentrations, the highest of 7 micrograms/kg occurring in a sample of bird food. Fumonisins were found in 30% of the 20 samples tested with a maximum of 750 micrograms/kg total fumonisins being found in a sample of cat food. Five samples each of dog and cat foods were examined for mould count and fungal species as received and after storage under controlled simulated damp conditions. Mould counts in all 10 samples examined were very low when received. The samples in which moisture content had been increased contained visible mould after storage. Penicillium, Eurotium and Aspergillus were the predominant species. However, no ochratoxin A or aflatoxins were detected in these spoiled samples.

Aflatoxins↗