Search PubMed⌕ Search

Biomedical subjects

J Nardi-Vilardaga

Publications and source records attributed to J Nardi-Vilardaga.

3 recordsLinked to original sources
PubMed1985

Embryonal hypermobility and articular development.

This investigation was devised to correlate development of the articular system of the embryo with variations of motility by introducing reserpine to chick embryos at a Hamburger-Hamilton stage 25-26. Administration of reserpine was followed by hypermotility or paralysis in a dose-dependent fashion. Size of joint cavities varies with motility of the limbs. Larger than normal cavities are due to excess movements, while lack of these impedes differentiation. These data are consistent with the primary role of motility in articular development.

Animals↗
PubMed1978

Influence of extrinsic factors on the development of the articular system.

In the present study, the results obtained after embryonic movements were paralyzed are described. Paralysis was produced by succinylcholine administered to chicken embryos during Hamburger-Hamilton's stages 25-29. The study of microscopic sections across all the articulations emphasize the absence of articular cavity formation. The cavities were replaced by a non-differentiated mass of mesenchymatous tissue. Regression of articular cavities and para-articular structures was noted in already formed embryos. Contrary to the opinion sustained by some authors, modifications on the articular surfaces were not produced. All of these data, reveal the importance of embryonic movements in articulation formation and conservation.

Animals↗