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Biomedical subjects

J N Williams

Publications and source records attributed to J N Williams.

At least 19 recordsLinked to original sources

Why is short-term sentence recall verbatim? An evaluation of the role of lexical priming.

By showing that short-term sentence recall can be significantly affected by words encountered in an intervening distractor task, Potter and Lombardi (1990, Journal of Memory and Language, 29, 633-654) argue that short-term sentence recall is often verbatim because of the availability of recently activated lexical entries during the regeneration of the sentence from its conceptual representation. We show that similar effects can be obtained even when bilinguals perform an intervening task in a different language from that of sentence recall, or when monolinguals perform an intervening task upon pictures. Furthermore, we show that the presentation of a word in P&L's distractor task does not, in any case, affect subsequent retrieval of a semantically related word as measured in a picture-naming task. We suggest that the effects on recall reported here and by P&L should be explained in terms of conceptual level interference at the time of recall. We also discuss the implications of our suggestion for the issue of the verbatimness of short-term sentence recall.

Analysis of Variance

Quality assessment/assurance activities in U.S. dental schools.

Quality of health care services has become a major social issue. Accordingly, activities directed toward the assessment and assurance of quality are receiving increased attention in dentistry and dental education. The purpose of this study was to determine the status of quality assessment/assurance (QA) programs in U.S. dental schools. Responses from 48 U.S. schools identify a range of institutional QA activities currently being conducted in dental education. The evaluation and remedial action elements of the QA process are being addressed in a majority of schools; however, the establishment of criteria delineating those elements of a given QA activity area that should be measured is lacking.

Education, Dental

Evaluating the anti-plaque capabilities of a copper-containing prophylaxis paste.

The purpose of this study was to evaluate a dental prophylaxis paste containing mono-copper citrate (MCC) for short term anti-plaque capabilities. In addition to other baseline data, plaque scores were recorded on 36 paid volunteer subjects from the dental school student, staff, and faculty populations. After scaling, two quadrants of each subject's dentition were polished with the MCC containing paste and two quadrants with the placebo paste, using a diagonal split mouth double blind design. Subjects did not brush or floss for two days. Plaque scores were recorded at 24 and 48 hours, after which they resumed normal hygiene. Results showed that after 24 hours placebo areas had 92% higher plaque and after 48 hours 33% higher plaque than the active paste areas. This was statistically significant at the P less than .001 level. The diminishing effect of the copper containing prophy paste over 48 hours might indicate that the copper ion should be applied on a daily basis for best anti-plaque results.

Citrates

Restoration of allograft responsiveness in B rats by interleukin 2 and/or adherent cells.

LEW X BN)F1 cardiac allografts survive 1 wk in unmodified LEW recipients (MST +/- SD = 8.3 +/- 1.2 days) but indefinitely (greater than 100 days) in B rats, produced by 750 R sublethal x-radiation 3 to 4 wk after adult thymectomy and reconstitution with syngeneic bone marrow cells from thymectomized thoracic duct-drained donors. Graft survival appears independent of blocking antibodies and is not mediated by suppressor cells or loss of graft immunogenicity. The unresponsive state is eventually reversed by adoptive transfer of 10(8) spleen cells from nonimmune (MST +/- SD = 27.5 +/- 4.7 days) or alloimmune (MST +/- SD = 21.5 +/- 1.9 days) syngeneic animals. In contrast, concomitant administration of 2 X 10(7) thioglycollate-stimulated peritoneal exudate adherent cells plus 10(8) alloimmune syngeneic spleen cells produced acute allograft rejection in 50% of B recipients within 10 to 12 days, while in every instance grafts underwent acute rejection (MST +/- SD = 10.0 +/- 1.4 days) in B recipients treated with interleukin 2 (IL 2) rich conditioned supernatant plus sensitized cells. In vitro studies revealed that adherent cells from B rats possessed less than 50% the capacity of adherent cells from normal animals either to support the Con A-stimulated uptake of 3H-thymidine by splenic T cells or to promote production of IL 2 by spleen cells depleted of adherent cells. Altered lymphocyte migration patterns in B recipients may also contribute to prolonged allograft survival secondary to adherent cell dysfunction.

Animals