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Biomedical subjects

J N Ventura

Publications and source records attributed to J N Ventura.

5 recordsLinked to original sources
PubMed1993

The effect of short term treatment with alendronate on vertebral density and biochemical markers of bone remodeling in early postmenopausal women.

The effects of oral alendronate treatment on spinal bone mineral density and biochemical markers of bone turnover were assessed in women in the early postmenopausal period. Sixty-five women were treated with placebo or 5, 20, or 40 mg alendronate daily for 6 weeks in a double blind study. Treatment with alendronate decreased both urinary markers of bone resorption (pyridinolines, hydroxyproline, and calcium) and serum markers of bone formation (osteocalcin and alkaline phosphatase) in a dose-dependent fashion. This short term treatment with alendronate also produced a dose-dependent increase in lumbar bone mineral density measured 7.5 months after the completion of therapy. Median percent changes in integral spinal bone mineral density, as assessed by dual x-ray absorptiometry, were -2.3, -1.2, +0.7, and +1.2 after treatment with placebo and 5, 20, and 40 mg alendronate, respectively. Treatment with alendronate was well tolerated and produced no fever; gastrointestinal intolerance was no more common than with placebo treatment. Short term alendronate treatment in early postmenopausal women decreased bone turnover and increased vertebral density.

Adult↗
PubMedDate not supplied

Parent coping, a replication.

Forty-seven pairs of parents of 2- to 3-month-old infants were asked to respond to a questionnaire to determine parent coping in relation to infant temperament and parent psychological responses. Mothers' and fathers' reports of helpfulness of coping behaviors were similar, but fathers reported more responses of depression and anxiety and focused less on coping by seeking social support and being responsible. Mothers who viewed their infant as of optimal temperament sought social support, maintained family integrity, and reported being religious, thankful, and content. Being responsible was more helpful to fathers who saw their infant as responding positively to soothing techniques and as smiling and laughing frequently, but less helpful to fathers who perceived their infant as being fearful and distressed by limitations. Fathers who perceived their infant as being fearful and distressed also reported more depression.

Adaptation, Psychological↗
PubMedDate not supplied

Parent coping behaviors, parent functioning, and infant temperament characteristics.

This study focuses on the relationship between parent coping behaviors, parent functioning, and infant temperament characteristics. One hundred mothers and fathers of two-to three-month-old infants answered a 154-item self-administered questionnaire. The following three parent-coping behavior patterns emerged: (1) seeking social support and self-development; (2) maintaining family integrity; and (3) being religious, thankful, and content. Parents who were depressed, anxious, and had somatic complaints perceived social support and self-development as more helpful and were less focused on maintaining family integrity. Parents who perceived their infant as having a more smiling, laughing temperament, and as a child who cries less, used coping behaviors designed to maintain family integrity; they were more religious, thankful, and content. Parents who were depressed and parents who were anxious saw their infants as less soothable and more distressed when faced with limitations.

Adaptation, Psychological↗