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Biomedical subjects

J Moore-Gillon

Publications and source records attributed to J Moore-Gillon.

26 records · Page 2Linked to original sources
PubMed1986

Fever during treatment of infective endocarditis.

In 83 episodes of culture-positive infective endocarditis (IE) of a native valve, fever persisted or recurred in 42 (50%) despite appropriate bactericidal antibiotics. The commonest cause of fever was extensive infection of the valve ring and adjacent structures, even when the infecting organisms were viridans streptococci; urgent surgery was required. Less frequent causes were systemic and pulmonary emboli and drug hypersensitivity. Infected intravenous access sites were seldom responsible. In no case was fever due to antibiotic resistance of the infecting organism. In patients with a definite microbiological diagnosis who have been given appropriate antibiotics, the temptation to alter antibiotic therapy because of persistent or recurrent fever should be resisted unless there are features of drug hypersensitivity. When fever persists or recurs during treatment of IE, the opinions of a cardiologist and cardiac surgeon should be obtained as soon as possible; delay in valve replacement may prove fatal in patients with extensive infection.

Acute Disease↗
PubMed1984

Necrobacillosis: a forgotten disease.

Over four years five previously healthy young adults developed necrobacillosis , a severe septicaemic illness caused by Fusobacterium necrophorum. The infections were characterised by sore throat followed by rigors and the formation of metastatic abscesses and all caused considerable diagnostic confusion.

Adolescent↗
PubMed1983

Prosthetic valve endocarditis.

During 1965 to 1982, 32 episodes of infective endocarditis on prosthetic valves in 30 patients were treated at this hospital. In early endocarditis (presenting within four months of operation) staphylococci were the organisms most commonly responsible. Early endocarditis appears to be declining in incidence and is largely preventable; sternal sepsis was the main predisposing factor, requiring urgent and effective treatment. Streptococci were the most common organisms in late onset disease, but as with natural valve endocarditis a wide range or organisms was responsible. All but one of the patients with early onset disease were treated conservatively, but mortality was high; prompt surgical replacement of infected prostheses is probably indicated in such patients. Medical management was effective in most patients with late onset disease, and for them early surgical intervention may not be justified.

Adult↗
PubMedDate not supplied

Respiratory disease in pregnancy.

Respiratory disease is common in pregnancy, and becoming more so: asthma, pneumonia and tuberculosis are all increasing in frequency. This review discusses these conditions and their relationship to pregnancy, as well as considering briefly some rarer diseases.

Female↗
PubMedDate not supplied

Asthma in pregnancy.

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Acute Disease↗