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Biomedical subjects

J Montgomery

Publications and source records attributed to J Montgomery.

At least 109 records · Page 6Linked to original sources
PubMed1987

Response of skin thickness and metacarpal index to estradiol therapy in postmenopausal women.

A radiologic method for measuring skin thickness and metacarpal index was used to investigate 41 postmenopausal women treated with estradiol (100-mg) subcutaneous implants (Organon, UK). All the women completed the first six months of the study, and 33 completed one year. Both skin thickness and metacarpal index increased to a statistically significant degree over the one-year period, with most of the increase occurring in the first six months of therapy. Skin thickness showed the largest increases, from a mean of 0.86 mm at the start of the study to 0.97 mm at six months and 1 mm at one year. The metacarpal index increased from a mean of 0.77 at the start of the study to a mean of 0.799 and 0.8 at six months and one year, respectively.

Estradiol↗
PubMed1986

Isolation of leptospires from the genital tract and kidneys of aborted sows.

Twenty sows were examined as part of an investigation into the relative importance of the genital and urinary tracts as sites of leptospiral persistence in pigs. The sows had previously either aborted leptospire-infected fetuses or aborted on farms where leptospire infection had been demonstrated in other litters. Leptospires belonging to the Australis serogroup were recovered from the upper genital tract of all the sows. In contrast, leptospires were only recovered from 75 per cent of their kidneys. Isolates from 10 of the sows were identified to serovar level: six were serovar muenchen and four were bratislava. Persistence was observed in renal and genital tissues for up to 147 days after abortion.

Abortion, Veterinary↗
PubMed1986

Prevalence of Leptospira interrogans serovar hardjo in the genital and urinary tracts of non-pregnant cattle.

In a bacteriological investigation of 60 cows and heifers from an abattoir Leptospira interrogans serovar hardjo was isolated from 39 (65 per cent) animals. The genital tract (57 per cent) appeared to be as important a site of hardjo localisation as the urinary tract (62 per cent). This is believed to be the first report of genital hardjo infection in naturally infected cattle.

Abattoirs↗
PubMed1985

Walking patterns of healthy subjects wearing rocker shoes.

We compared walking in rocker shoes with walking in athletic shoes at free and fast velocities in 15 healthy women who were between the ages of 21 and 30 years. Footswitches, electrogoniometers, surface electromyograms, and a force plate were used for data collection. No significant differences were found in velocity, cadence, gait-cycle duration, single-limb support, or swing-stance ratios in free and fast walking. Double-limb support was decreased by 9% in the rocker shoes in free walking. The ankle range of motion showed accommodation of the foot to the 8.5 degrees of plantar flexion built into the rocker shoes. Electromyographic responses appeared to be similar regardless of shoes or cadence.

Adult↗
PubMed1985

Dihydrostreptomycin treatment of bovine carriers of Leptospira interrogans serovar hardjo.

Ten non-pregnant heifers, experimentally infected with Leptospira interrogans serovar hardjo, were each given an intramuscular injection of dihydrostreptomycin at a dose rate of 25 mg kg-1. In five of these animals this treatment was repeated after 14 days. Treatment failed to remove established genital or renal infection in seven of the 10 heifers, although the number of organisms persisting was apparently reduced in these animals. Serovar hardjo infection persisted for at least 83 days in the oviduct and uterus and these tissues may be as important carrier sites for serovar hardjo as bovine kidney tissue.

Animals↗
PubMed1985

The aetiology of purulent meningitis in highland children: a bacteriological study.

Of 155 highlands children with purulent culture-positive meningitis studied from March 1980 to September 1984, 84% were aged twelve months or less and 92% were infected with either Haemophilus influenzae, Streptococcus pneumoniae or both organisms. Other pathogens were Neisseria meningitidis (8 isolations), Streptococcus pyogenes (2 isolations) and Streptococcus agalactiae and Klebsiella species (1 of each). Among H. influenzae isolates, serotype b strains predominated (83%) and most (96%) belonged to biotype I or II. Infections due to non-b haemophili included serotype a (9 strains), serotype f (1 strain) and non-serotypable variants (3 strains). Of 67 S. pneumoniae strains 22% were resistant to benzylpenicillin, with minimal inhibitory concentrations of 0.1-1.0 micrograms/ml. The commonest serotypes were types 5 (11 isolates), type 7 (9 isolates) and types 2, 6 and 46 (6 of each). No resistance to chloramphenicol was detected in either H. influenzae or S. pneumoniae and only one of 56 strains of H. influenzae was insensitive to betalactam antibiotics. The known case fatality rate in this study was 37%. More children with pneumococcal infection died (46%) than those with haemophilus infection (30%), though the difference was not statistically significant; 79% of all deaths occurred in children aged less than twelve months. There is an urgent need for H. influenzae and S. pneumoniae vaccines that are effective in young children.

Age Factors↗
PubMed1985

The aerobic bacteriology of infected skin lesions in children of the Eastern Highlands Province.

Of 480 children studied, the relative frequency of skin infections divided into three categories were: score 266 (55%), infected scabies 164 (34%) and tropical ulcers 50 (10%). Infected scabies was more prevalent in the less than 2 year age group and tropical ulcers were commonest in the 9-12 year age group and these differences were significant. The majority of lesions occurred on the lower extremities with the trunk the least commonly affected area. No significant differences were found in different age groups between males and females. Beta haemolytic streptococci (95%), Staphylococcus aureus (83%), Corynebacterium diphtheriae (72%) and Corynebacterium haemolyticum (35%) were the major bacteria isolated. Beta haemolytic streptococci were the most prevalent in infected scabies and least in tropical ulcers and these differences were significant. Three major Lancefield groups were isolated: group A (61%), group C (19%) and group G (19%). The distribution of these groups were unequal with group A most common in infected scabies but rarely seen in tropical ulcers. Groups C and G were found more commonly in tropical ulcers than the other two groups of lesions and these differences were significant. Multiple populations of beta haemolytic streptococci in a single lesion were seen in 19% of children. Less than one third of Streptococcus pyogenes were M typable and of these 18% were known nephritogenic serotypes. Staphylococcus aureus was significantly more common in infected scabies and least common in tropical ulcers. The prevalence of Vincent's organisms in tropical ulcers (74%) was significantly higher than scores (9%) and infected scabies (1%). The isolation rate of Corynebacterium diphtheriae was significantly higher in infected scabies than the other two groups. The most common biotype isolated was var mitis (72%). Only 2% of isolates were toxigenic. Corynebacterium haemolyticum was isolated significantly more frequently in tropical ulcers than the other lesions. All major bacteria, excluding betalactamase-producing Straphylococcus aureus, were uniformly sensitive to penicillin. Methicillin resistance was found in 1% of Staphylococcus aureus isolates and is reported here for the first time in this country. These isolates were also multiply resistant to erythromycin, chloramphenicol and tetracycline.

Anti-Bacterial Agents↗
PubMed1984

Pathogens detected in the faeces of children with diarrhoea in a Sydney hospital.

During a 54-week period, faecal samples taken from 350 children under 5 years of age, who were admitted with acute diarrhoea to the infectious diseases ward of a Sydney hospital, were examined for pathogens. Rotavirus was detected as the sole agent in the specimens of 58 patients (16.6%), enteroviruses in those of 26 patients (7.4%), salmonellae in those of 19 patients (5.4%) and Campylobacter jejuni in those of 15 patients (4.3%). Shigellae were not detected. The results are discussed and, in view of the changing patterns of infection, it is suggested that there is a continuing need for research into the causes of enteritis in Australia.

Australia↗
PubMed1984

Distribution and relationship to serotype of Haemophilus influenzae biotypes isolated from upper respiratory tracts of children and adults in Papua New Guinea.

The relationship between serotypes and biotypes of 505 carriage strains of Haemophilus influenzae isolated from the upper respiratory tracts of well children, children with pneumonia, and healthy adults was studied. All except serotype c were significantly associated with one or two specific biotypes (P less than 0.001). No encapsulated organisms belonging to biotypes V, VI, or VII were encountered. No significant difference in the interaction of biotypes and serotypes isolated from well and sick children was present. Both encapsulated and nonserotypable biotype I H. influenzae strains were commonly carried in the upper respiratory tracts of healthy Melanesian children. The distribution of nonserotypable H. influenzae strains occurred throughout all biotypes, and the frequency of nonencapsulated biotype III and IV strains differed significantly from serotypable organisms with the same biotype (P less than 0.001).

Adult↗
PubMed1984

Carriage of Corynebacterium diphtheriae in children of the Eastern Highlands province.

The incidence of Corynebacterium diphtheriae in infected skin sores and the nasopharynx of 99 children from the Asaro Valley in the Eastern Highlands is reported. C. diphtheriae was isolated from 88% of skin sores and 26% of nasopharyngeal swabs. The most common biotype seen was C. diphtheriae var mitis. Toxigenic strains were uncommon, occurring in 5% of skin lesions and 15% of nasopharyngeal swabs. All isolates were sensitive to penicillin, erythromycin and chloramphenicol.

Carrier State↗
PubMed1984

The bacteriology of skin sores in Goroka children.

The bacteriology of infected skin lesions was studied in paediatric outpatients. Thirty-nine untreated lesions were studied: 37 (95%) grew beta haemolytic streptococci (46% group A, 3% group B, 23% group C, 26% group G), 21 (54%) grew Staphylococcus aureus and 13 (33%) grew Corynebacterium haemolyticum. No attempt was made to selectively isolate Corynebacterium diphtheriae in this study. Vincent's organisms were seen in 13 (37%) of 35 gram stains from untreated lesions, including eight (73%) of 11 tropical ulcers. Twenty-three (92%) of the 25 strains of S. aureus isolated from untreated sores were resistant to penicillin.

Child↗
PubMed1983

Apparent gastrointestinal origin of cis-4-hydroxycyclohexanecarboxylic acid.

We identified by gas chromatography-mass spectrometry the unusual substance cis-4-hydroxycyclohexanecarboxylic acid (4-HCH) in the urine of a child. Urinary excretion of 4-HCH and intestinal bacteria were both suppressed by neomycin treatment. We propose that 4-HCH is a by-product of bacterial metabolism.

Bacteria↗
PubMed1983

The effect of manipulating phonation duration on stuttering.

Two single-subject experiments with two adult stutterers were conducted to assess the effect of changing the frequency of phonation intervals that were shorter or greater than prescribed durations during spontaneous speech. Both subjects modified the frequency of prescribed phonation intervals and showed changes in the frequency of these intervals that were positively related to decreases and increases in stuttering frequency. A perceptual analysis of the subjects' speech quality during phonation control conditions showed that when stuttering frequency was reduced, listeners could detect changes in the speech quality of both subjects; however, only one subject's speech during these conditions was described as nonnormal sounding. The therapeutic and theoretical implications of these findings are discussed.

Adult↗