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Biomedical subjects

J Montagut

Publications and source records attributed to J Montagut.

10 recordsLinked to original sources
PubMed1994

[The incidence of second neoplasms in advanced laryngeal cancer. Impact on survival].

BACKGROUND: The incidence of second neoplasms in laryngeal cancer is greater than that of other neoplasms. The appearance of a second neoplasm in these patients represents an important decrease in survival. The prevalence of second neoplasms in laryngeal cancer and its impact on survival was determined in this study. METHODS: Seventy-eight patients with advanced laryngeal cancer (stages III and IV of the UICC) who had been treated with erradicative surgery from January 1984 to December 1988; and who were attended in the Radiotherapy and Oncology Department of the Ciutat Sanitària i Universitària Vall d'Hebron were retrospectively studied. All were postoperatively submitted to radiotherapy. RESULTS: Ten of the 78 patients studied (13%) developed a second neoplasm. The most frequent localization was pulmonary (70%). In 9 of the 10 patients the appearance of the second neoplasm was considered metachronic with 60% being detected within the first 24 months after the diagnosis of the laryngeal neoplasm. The survival of the whole group was 80% at 2 years and 51% at 5 years. Survival of the patients with the second neoplasm was lower: 71% at 2 years and 5% at 5 years (p < 0.0001). CONCLUSIONS: The presence of a second neoplasm in patients with laryngeal cancer is high. The survival of patients with advanced laryngeal cancer who develop a second neoplasm is significantly lower than that of other patients with this neoplasm.

Adult↗
PubMed1991

Slide Flask direct amniotic fluid cultures.

Slide Flask direct amniotic fluid culture enabling: to decrease the risk of abnormalities caused by the technique itself, to facilitate laboratory work, to shorten culture time (8 to 13 days).

Amniotic Fluid↗
PubMed1990

[Presence of caries and periodontal disease in Spanish students. Overview of results obtained in different localities].

Results of our survey in 11 locations of Spain are assembled in an overview showing percentages of persons according to the highest C.P.I.T.N. code defected for each one, the prevalence of caries-free-children and mean D.M.F.T. scores. We have also studied the differences between urban and rural populations. Rural children presented higher D.M.F.T. an D.T. scores.

Adolescent↗
PubMed1988

Are clinical and biological IVF parameters correlated with chromosomal disorders in early life: a multicentric study.

A multicentric study was carried out to analyse in a large series: (i) the chromosomal status of unfertilized oocytes, (ii) errors at fertilization and (iii) the chromosomal complement of cleaved embryos. Parameters such as type of sterility, maternal age, stimulation treatment, doses of gonadotrophins administered and oocyte preincubation time before insemination were studied in relation to the incidence of chromosome abnormalities. Twenty-six per cent of the unfertilized oocytes and 29.2% of the embryos had chromosome anomalies. Maternal age significantly increased the rate of aneuploidy in oocytes: 38% in patients over 35 years (versus 24% in younger patients). Fertilization-related abnormalities were significant, i.e. 1.6% parthenogenesis and 6.4% polyploidy. Unexplained infertility was correlated with an increase in the rate of parthenogenesis (4.2%) when compared with tubal infertility (1.2%). Triploidy was found to be correlated with three parameters. A lower rate of triploidy was observed in the group of couples referred because of male sterility (1.9% versus 6.3% for tubal sterility), in HMG-treated patients (2.4% versus 7% with analogues of LHRH/HMG) and with a short 2-h preincubation time before insemination (3% versus 7.2% for greater than 2 h). A general model for natural selection against embryos carrying a chromosome imbalance was proposed.

Chromosome Aberrations↗
PubMed1981

Evaluation of some platelet parameters in a group of elderly people.

Platelet production time (PPT), plasmatic beta-thromboglobulin (beta-TG), platelet density distribution, and mepacrine labelled granular content of the platelets were simultaneously determined in a group of elderly subjects. Vascular deterioration, assessed by the history and clinical examination, was variable in extension and severity. PPT was slightly but not significantly shortened, whereas the raised beta-TG level and diminished platelet density and granular content suggested an in vivo release reaction process. The results are not correlated with the apparent severity of vascular deterioration, and the release reaction may not be solely related to enhanced platelet-vessel wall interactions.

Adult↗
PubMed1981

Cutaneous cholesterol and plasma lipoproteins in elderly active and bedridden patients compared with young adults.

This report concerns two groups of elderly patients, one active and the other inactive with cardiovascular histories. Cutaneous and plasma cholesterol (Ch) and the lipoprotein fractions were analyzed in each group and compared with those of a young group. The cutaneous histological ageing type was studied in the three groups. No histological difference was seen to exist between the elderly populations (skin type II), the young group had normal type O skin. A significant difference was seen to exist between the levels of cutaneous Ch of the two elderly groups and that of the young group. Changes in the cutaneous Ch with respect to the ratio (total Ch/HDL Ch) were found to differ in the two elderly groups: the active elderly patients presented a positive correlation as did the young subjects but the inactive patients showed a negative correlation.

Adult↗
PubMedDate not supplied

[Treatment of severe urinary infection in the elderly. Clinical and bacteriological study of 130 cases (author's transl)].

Strict criteria were applied in the choice of the 130 patients with severe urinary infections included in the study: men or women over 65 years of age presenting with clinical signs and symptoms, a bacterial count greater than or equal to 10(6)/mm3, one type of germ found on urine culture. The results of an antibiogram showed the frequency with which each germ was involved and their sensitivity to antibiotics, more particularly gentamicin, minocyclin, sulphamethoxazole-trimethoprime, oxolinic acid. Based on sensitivity and tolerance criteria, the choice of antibiotic was : oxolinic acid orally ; gentamicin parenterally, after evaluation of renal function. These results can assist the physician, when confronted with cases of severe urinary infection, and before the results of the antibiogram are available, in choosing effective therapy adapted to each case.

Aged↗