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Biomedical subjects

J Molcan

Publications and source records attributed to J Molcan.

At least 19 recordsLinked to original sources
PubMed1990

[Eglonyl in the treatment of schizoaffective psychoses].

The author investigated in an open clinical study the neuroleptic and antidepressive action of Eglonyl in 17 patients who met the criteria (diagnosis of psychoaffective psychosis, symptoms in the sphere of schizophrenia, depressive pathic moods). Eglonyl was administered by injection during the first four days and in tablet form on the subsequent 24 days in individual daily doses of 300-800 mg. At the onset and after 7-day intervals the patients were followed up, by clinical and psychiatric tests, along with the evaluation of the therapeutic effect by means of the clinical global impression scale, CGI, by the BPRS scale, and side-effects by means of the SARS scale. For statistical analysis Wilcoxon's test was used. The expected neuroleptic and antidepressive action of Eglonyl was confirmed in the clinical trials in patients with schizoaffective psychosis--depressive type: marked improvement was recorded in 58.9% of patients, medium improvement in 29.4% and slight improvement in 11.7% of patients. The decline of the global score in BPRS is highly significant (T1 - Tpop = 76.5, P less than 1%).

Adult↗
PubMed1989

[Hospitalization of minors at a psychiatric clinic for adults].

The authors analyzed the case-sheets of 45 minors examined and treated in departments for adults at the Psychiatric Clinic, Medical Faculty Comenius University, Bratislava in 1974-1980. The patients comprised 21 girls and 24 boys. Sixty-two case-sheets were analyzed because of repeated hospital admissions. Forty-three hospitalizations concerned adolescents aged 16-17 years. During the last two years of the observation an increase of enforced hospital admissions associated with suicidal attempts and drug dependence was observed. Suicidal attempts occurred in 23.2% of the cases and were demonstrative, affective and seriously meant according to A. E. Licek's classification. All hospital admissions were necessary, frequently urgent and life saving. Hospitalization of adolescents in departments for adults is not an optimal variant of specialized care of youth.

Adolescent↗