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Biomedical subjects

J Michel

Publications and source records attributed to J Michel.

At least 217 records · Page 12Linked to original sources
PubMed1975

Antimicrobial activity of human peritoneal fluid.

Cell free peritoneal fluids from 23 normal women had antimicrobial activity which was directed against gram-positive and gram-negative bacteria and also against yeasts. The activity was bacteriostatic or bactericidal and seemed to be due to the presence of a variety of factors which varied in their heat stability and dependence on complement. Lysozyme was present in the fluids but was not responsible for all the antimicrobial activity.

Ascitic Fluid↗
PubMed1973

Bactericidal effect of combinations of nalidixic acid and various antibiotics on Enterobacteriaceae.

The activity of nalidixic acid combined with each of 10 other antimicrobial agents on 95 strains of Enterobacteriaceae was studied. Synergism was found less often than antagonism, and the commonest outcome was indifference. Combinations of nalidixic acid with kanamycin, gentamicin, or colistin were more often synergistic than antagonistic, whereas with the other antibiotics the combination was more often antagonistic than synergistic. Synergistic effects were more common with Shigella than with other genera. In vitro examination for synergism or antagonism appears to be advisable before nalidixic acid is used therapeutically in combination with other antimicrobial agents.

Anti-Bacterial Agents↗