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Biomedical subjects

J Mi

Publications and source records attributed to J Mi.

24 records · Page 2Linked to original sources
PubMed1999

[The relation of fetal growth and the biological risk factors of coronary heart disease].

OBJECTIVE: To examine the relationship between fetal growth and the biological risk factors of coronary heart disease (CHD) in adult life in China. METHODS: Follow up stuty of 628 men and women who were singleton born during 1948-1954 whose birth size were measured in detail. RESULTS: Decreasing birth weight increased the probability of myocardial ischaemic symptom related to CHD (beta = -0.0018, P < 0.01). The Odds ratio (OR) related to hypertension increased with decreasing birth weight and ponderal index (PI, kg/m3). The OR were 5.9 in people whose PI were 24 kg/m3 or less compare to people whose PI were more than 28 kg/m3. The OR related to impaired glucose tolerance(IGT) also increased with decreasing birth weight and PI. Insulin resistance, represented by fast insulin, rose with decreasing birth weight and head circumference(for trend, all P < 0.01). Serum TG concentration significantly rose with decreasing birth weight, PI and head circumference (for trend, P < 0.01, P < 0.01, P < 0.05), while HDL-C rose with increasing birth weight and head circumference (for trend, P < 0.05, P < 0.01). All above mentioned relations between birth size and the level of risk factors during adulthood were independent of gestation and adult lifestyle. CONCLUSIONS: In China, low birth measurements which represent the fetal growth retardation might contribute to the present of biological risk factors of coronary heart disease during adulthood, such as hypertension, diabetes, insulin resistance, high serum triglyceride and low HDL-C.

Birth Weight↗
PubMed1994

Extensive anterior decompression for mixed cervical spondylosis. Resection of uncovertebral joints, neural and transverse foraminotomy, subtotal corpectomy, and fusion with strut graft.

STUDY DESIGN: This study examined a new operative procedure for treating mixed cervical spondylosis. OBJECTIVES: To relate postoperative results with extensive decompression using a surgical microscope. SUMMARY OF BACKGROUND DATA: Based on the dissection cadavers and clinical practice, extensive anterior decompression has been designed for mixed cervical spondylosis. It has not been reported that the cervical cord, nerve roots, and vertebral arteries have been decompressed thoroughly at the same time. METHODS: Fifteen patients with mixed cervical spondylosis were treated with extensive anterior decompression using an operative microscope. The pathologic segments in all patients were identified preoperatively with cervical radiography, myelography, computed tomography, computed tomographic myelography, and magnetic resonance imaging. The Japanese Orthopaedic Association classification was used to assess the follow-up results. The operative results demonstrated the efficacy of the surgical approach. RESULTS: All patients improved neurologically, with the average Japanese Orthopaedic Association score improving from 6.3 points preoperatively to 12.4 points at follow-up examination. The plain radiography, computed tomography, and magnetic resonance imaging follow-up examination showed that the anterior part of the cervical canal and the transversaria or neural foramina were enlarged, and that there was satisfactory bony fusion without signs of nonunion and other complications. CONCLUSIONS: Extensive anterior decompression (resection of uncovertebral joints, neural and transverse foraminotomy, subtotal corpectomy, and fusion with strut graft), a new surgical procedure for treating mixed cervical spondylosis, led to excellent follow-up results.

Adult↗
PubMed1992

[Construction and identification of vectors containing maize plasmid-like DNA S1 and reporter genes].

The reporter Gene GUS with CaMV 35S promoter was inserted into plasmid pBS[1] in reversal direction of integration, and two kinds of recombinant plasmids were obtained. These results were verified by restriction endonuclease analysis and southern hybridization. A piece of 10.8kb fragment containing NPT II reporter gene from digested pBI121.1 by BamHI and EcoRI was ligated together with 3.9 kb fragment of plasmid-like DNA S1. Then generate a recombinant plasmid pBIS5 was generated. These three vectors can be used to transform maize protoplasts. High frequency of transformation may be expected due to homology between plasmid-like DNA S1 and maize nuclear DNA.

DNA↗