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J Merino Angulo

Publications and source records attributed to J Merino Angulo.

At least 37 records · Page 2Linked to original sources

Tubular aggregates in skeletal muscle of chronic alcoholic patients.

The presence of tubular aggregates (TA) in type II muscle fibers in two of 20 alcoholic patients with chronic liver disease, and with no apparent neuromuscular disorder, is reported. The localization, histochemical reactions, and ultrastructural features of the TA are similar to those previously described in other conditions. In one of the two cases TA were demonstrated by E/M observations only and not by histochemistry. No correlations were found between the biochemical changes and the presence of tubular aggregates. We believe that TA are long-standing structures since the muscle biopsies were performed 12 and 13 days after the ingestion of alcohol had been discontinued. They may represent a non-specific response of the sarcoplasmic reticulum to compensate for the deficient calcium uptake reported in alcoholic patients.

Adult↗

[Unusual forms of Fasciola hepatica infestation. Report of two cases (author's transl)].

Infestation by Fasciola hepatica is being reported with increasing frequency. During a five year period the authors have studied 25 cases of disease caused by F. hepatica, all of them diagnosed by finding eggs of the parasite in the feces or the duodenal fluid. In two cases the ectopic location of th parasite gave rise to unusual clinical manifestations. The first case presented during the course of hepatic fascioliasis both subcutaneous and epididymis locations, with an histologic picture similar to that of the hepatic lesions. The involvement of the epididymis, not previously cited in the literature, gave rise to a hydrocele. The second case presented with signs of central nervous system involvement and a high eosinophil count in the cerebrospinal fluid. Dehydroemetine was effective in all patients, including the unusual cases.

Adult↗