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Biomedical subjects

J Mercier

Publications and source records attributed to J Mercier.

At least 235 records · Page 13Linked to original sources

[Gas gangrene of dental origin. Report on four cases (author's transl)].

Four patients developed diffuse cervicofacial cellulitis following an acute circumscribed infection of dental origin. Necrosis of skin, subcutaneous and muscle layers was associated with a severe generalised toxic infective syndrome, producing a clinical picture and following a course identical with that observed in gas gangrene of the limbs. Anaerobic germs, normally present in the buccodental region, were at the origin of the affection in all four cases, chronic dental lesions providing favourable anaerobic conditions for an increase in their virulence. Three factors appear to be of importance for the development of gas gangrene from dental abscesses: insufficient or lack of suitable surgical treatment, the use of antibiotics not active against anaerobic germs, treatment with corticoids or anti-inflammatory drugs. Once gas gangrene has developed, possible intramediastinal spread should be investigated. Treatment is essentially surgical (with excision of necrotic tissue and wide drainage), plus penicillin therapy and hyperbaric oxygen. The prophylaxis of these gas gangrene lesions is discussed.

Adult↗

[Results of treatment of mandibular fractures in 27 children (author's transl)].

Twenty-seven children aged from 0 to 15 years were treated for mandibular fractures in the Stomatology and Maxillofacial Surgical Unit in Nantes over a period of three years. Fractures of the condyle were frequently observed. Good results were obtained with functional treatment, but very strict criteria should be applied when assessing the quality of these results (which should be excellent, especially in relation to condylar mobility, in young subjects during the growing period).

Adolescent↗

[Effect of isoprenaline, in mice anesthetized with pentobarbital, on the cerebral concentration of barbiturates and on the blood levels of free fatty acids].

In mice isoprenaline increases duration of pentobarbital narcosis without modification of cerebral levels. A correlation between duration of sleep and FFA seric levels increased by isoprenaline is demonstrated. This dual effect is suppressed by pindolol. These facts suggest that hepatic metabolism of pentobarbital is slowed by lipo-mobilisation.

Animals↗