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Biomedical subjects

J McMurray

Publications and source records attributed to J McMurray.

125 records · Page 7Linked to original sources
PubMed1987

Consequences of fluid loss in patients treated with ACE inhibitors.

Three patients are described in whom haemodynamic collapse and acute renal failure occurred following intercurrent gastrointestinal fluid loss during treatment with an angiotensin converting-enzyme inhibitor. The possible consequences of blockade of the formation of angiotensin II during fluid loss are discussed.

Acute Kidney Injury↗
PubMed1986

Association between liberalization of Scotland's liquor licensing laws and admissions for self poisoning in West Fife.

Data were collected prospectively on 2868 consecutive patients admitted for self poisoning between 1971 and 1982. Analysis showed a dramatic increase in the frequency of alcohol taken in association with self poisoning, in both sexes, after the liberalization of Scotland's liquor licensing laws. This increase, however, did not appear to affect the severity of overdoses or the outcome. Total admission rates for self poisoning increased with relaxation of the liquor licensing laws, and since overdoses associated with alcohol tend to occur at night these impose considerable strain on casualty departments and acute admitting units.

Alcohol Drinking↗
PubMed1986

Pneumonia.

Explore the source record for details and available documents.

Humans↗
PubMed1985

Changes in erythrocyte transketolase activity and the thiamine pyrophosphate effect during storage of blood.

Whole blood and washed erythrocytes from nutritionally normal and abnormal elderly patients were stored at room temperature, 4 degrees C and -20 degrees C for up to 14 days. In both groups, and under all storage conditions, the erythrocyte transketolase (ETK) activity and the thiamine pyrophosphate (TPP) effect decreased with time of storage. The ETK activity for specimens stored at -20 degrees C decreased significantly by day 14 (P less than 0.05). The TPP effect in specimens stored at -20 degrees C decreased significantly in the nutritionally abnormal group at 4 days (P less than 0.05) and in the nutritionally normal group by day 14 (P less than 0.05). These significant changes in ETK activity and TPP effect with storage can lead to misleading interpretation of thiamine nutritional status.

Aged↗
PubMed1979

Plasma 25-hydroxyvitamin D in pregnant Asian women and their babies.

Plasma 25-hydroxyvitamin D (25-OHD) was measured in cord blood taken at delivery and in fasting blood taken from 44 Asian mothers in the first day of the puerperium. Blood was taken from the baby 48 h after delivery. Cord-blood samples were also taken at 43 non-Asian deliveries. Plasma 25-OHD concentrations in Asians were low at delivery; in 81% of the mothers and 36% of the babies plasma 25-OHD was in the osteomalacic range. Asian lower than concentrations in non-Asian controls. 4 Asian babies had vraniotabes and 1 had neonatal tetany. 1 non-Asian baby had craniotabes. A review of 3327 deliveries in 1978 confirmed that neonatal tetany was significantly more common in Asian babies (2.3%) than in non-Asian babies (0.3%). In 44 other Asian mothers supplements of 1000 units of vitamin D daily during pregnancy significantly increased plasma-25-OHD concentrations at delivery.

Asia↗
PubMed1975

The effect of cerebral dominance on time sharing between speaking and tapping by preschool children.

48 kindergartners tapped as fast as they could with either the right index finger or the left, either alone or while reciting or repeating verbal material. The secondary tasks diminished tapping rate on both sides, but disproportionately on the right. This result was predicted by a model that postulates greater interference between concurrent activities when both are programmed by the same cerebral hemisphere. Children appear to be more vulnerable to this type of interference than adults. This attribute of immature motor development can be used as an indicator of cerebral lateralization of function in children.

Age Factors↗
PubMedDate not supplied

Problems solved and lives saved? Chronic heart failure.

Chronic heart failure (CHF) is common, disabling and deadly. Recent studies show that ACE inhibitors reduce morbidity and mortality in all grades of CHF and may even delay or prevent the onset of overt CHF in patients with asymptomatic left ventricular dysfunction. In this review, guidelines are given for how to use these drugs both in hospital and in general practice. New evidence on the benefits of digoxin is also considered, and the management of concomitant problems such as angina and arrhythmias in patients with CHF is discussed.

Angiotensin-Converting Enzyme Inhibitors↗