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Biomedical subjects

J Matsuyama

Publications and source records attributed to J Matsuyama.

26 records · Page 2Linked to original sources
PubMed1995

[ACTH producing pituitary adenoma with multiple intracranial metastases and spinal dissemination].

A 34-year-old male developed multiple intracranial and intraspinal metastases from an invasive ACTH secreting pituitary adenoma. He was initially admitted to our hospital complaining of visual loss 10 years ago, presenting a pituitary tumor with suprasellar extension. At first, transsphenoidal surgery was performed, and histological finding was pituitary apoplexy. He developed recurrence of the tumor 2 times. At the second, third and fourth operation, the histological finding was an ACTH secreting pituitary adenoma with atypia. Metastases within the central-nervous system of pituitary adenoma is a rare entity and only 21 cases have been published. A review of previously published cases follows.

Adenoma↗
PubMed1993

A case of Sjögren's syndrome complicating immune-mediated aplastic anaemia.

A 78-year-old Japanese woman with Sjögren's syndrome complicating immune-mediated aplastic anaemia is described. A diagnosis of aplastic anaemia was made from severe pancytopenia with hypoplastic marrow. Laboratory studies suggested an association of bone marrow suppressive T-lymphocytes with the pathogenesis of aplastic anaemia. Following the administration of mepithiostan and prednisolone, pancytopenia improved gradually. Two years after the onset of aplastic anaemia, Raynaud's phenomenon developed and examinations revealed the existence of keratoconjunctivitis sicca and anti-SSA/Ro and anti-SSB/La antibodies.

Aged↗
PubMed1991

Identity of hemolysins produced by Bacillus thuringiensis and Bacillus cereus.

A hemolysin (Bt-hemolysin) produced by Bacillus thuringiensis var. kurstaki HD-1 producing crystalline toxin(s) was purified by successive treatments of ammonium sulfate (45-65%) and column chromatography using DEAE-cellulose, Sephadex G-75 and KB-002 (a hydroxyapatite column for fast protein liquid chromatography). A hemolysin (Bc-hemolysin) produced by B. cereus HG-6A was also purified by the same procedure. The purified Bt-hemolysin and Bc-hemolysin, both of which are thiol-activated hemolysins, were biologically, physicochemically and immunologically identical. These findings provide further evidence of the similarity of B. thuringiensis, which is being used as a biological insecticide, to B. cereus, a toxigenic organism of food poisoning.

Bacillus cereus↗
PubMed1990

[Clinico-statistical observation of the dental surgery in the pedodontics clinic of Niigata University Dental Hospital during the period from 1979 to 1989].

Clinico-statistical observation was performed on the dental surgery in the Pedodontic Clinic of Niigata University Dental Hospital during the period from August 1979 to September 1989. 1. The number of surgical operations amounted to 656 cases (males 384 and female 272) and the highest age incidence was in the 6-8 year old range. 2. The incidence of the impacted teeth (62.8%) and the abnormality of the frenum (22.8%) occupied over 85% of all the cases. 3. Based on sex, the impacted supernumerary teeth and the abnormality of the buccal frenum, odotoma were more frequent in males, while the abnormality of the upper frenum and the mucous cysts were more frequent in females. 4. About 40% of the operative patients accepted were introduced from other medical institutions. 5. Regarding the methods of surgery, the impacted permanent teeth were frequent revealed by surgical exposure, while the diseases of salivary glands were revealed by extirpation. The benign tumors were removed by extirpation, the diseases of soft tissues by excision, cysts in the jaws were all surgically removed by marsupialization. 6. In regard to the age at the time of the operation, the abnormal frenum were often seen under 4 years of age but large increases were found in the impacted teeth from 4 to 8 years of age. The diseases of salivary glands and of soft tissues were seen more frequently under 10 years of age, and cysts in the jaws were noted after 7 years of age. 7. Children undergoing surgery who suffered from general diseases amounted to 31 cases and were found most commonly in cases of nervous mental diseases.(ABSTRACT TRUNCATED AT 250 WORDS)

Age Factors↗
PubMed1989

[Gliosarcoma with multiple extracranial metastases. Case report].

A 68-year-old male was hospitalized because of headache, nausea, and disturbance of consciousness. Neurological examination on admission disclosed somnolence, disorientation, marked neck stiffness, papilledema, and quadriparesis. Computed tomography (CT) scanning demonstrated a round mass with marked contrast enhancement in the right sylvian fissure and small contrast-enhanced masses in the interpeduncular, quadrigeminal and ambient cisterns. CT also showed marked peritumoral edema, a midline shift, and hydrocephalus. The patient's consciousness level and respiration deteriorated 3 days after admission and a craniotomy was performed. The tumor, which was well demarcated, firmly attached to the sphenoidal ridge, and grossly appeared to be a meningioma, was totally removed. Histologically, the tumor had two well defined components, glioblastoma and fibrosarcoma. The patient underwent ventriculoperitoneal shunting, chemotherapy, and radiotherapy after surgery, but the primary tumor soon recurred, with scalp metastasis, and he died 5 months postoperatively. Autopsy revealed metastases to the liver, spleen, and spinal cord. The histogenesis of this mixed tumor and the mechanism of extracranial metastasis are discussed, and the literature is reviewed.

Aged↗
PubMedDate not supplied

Fermentation of five sucrose isomers by human dental plaque bacteria.

Sucrose has five structural isomers: palatinose, trehalulose, turanose, maltulose and leucrose. Although these isomers have been reported to be noncariogenic disaccharides, which cannot be utilized by mutans streptococci, there is no information about their fermentability by other bacteria in dental plaque. The purpose of the present study was to examine whether these isomers were fermented by predominant bacteria in human dental plaque. Clinical bacterial isolates obtained from dental plaque from 3 children aged 22 months to 50 months (146 strains) were inoculated into 3 ml of peptone-yeast extract (PY medium) containing glucose for 1 day, then an aliquot of 20 microl of culture medium was inoculated into 1 ml of PY medium containing 1% (w/v) of the respective test carbohydrates. After incubation for 1 day, the pH values and the optical density at 660 nm of the cultures were measured. Fermentation ability was measured by pH or=0.5. Of the clinical isolates, 33% fermented palatinose, and 69% of these were Actinomyces species. All of the palatinose-fermenting bacterial strains fermented trehalulose, 25% fermented turanose, 70% fermented maltulose and 23% fermented leucrose. We therefore conclude that, in human dental plaque, there are significant numbers of bacteria that are able to ferment sucrose isomers.

Actinomyces↗