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Biomedical subjects

J Markwardt

Publications and source records attributed to J Markwardt.

9 recordsLinked to original sources

[Possibilities of using monoclonal antibodies to CEA in scintigraphic diagnosis of tumors].

Improved tumour localization by scintigraphy is the aim of application of radiolabelled antibodies in nuclear medical tumour diagnostics. Results from the literature until 1984 in the field of monoclonal antibodies (Mabs) against CEA are discussed in the following points: type and stability of the radiolabelling; accumulation and biologic activity of Mabs in the animal; distribution of Mabs in clinical application and possible injury for the patient; methods for increased accumulation in the tumor and improved tumour-imaging. Further work is needed in this field before introducing this method into the diagnostic routine.

Animals

[Abortive duplication of the gut (author's transl)].

Presentation of a case of intestinal duplication sited in the rectosigmoid colon. Rectosigmoid colon and duplication were coated with gastric mucosa. Diagnosis of heterotopic gastric mucosa was done by biopsy and 99mTc-pertechnetate scintigraphy. The diseased colon was removed by Rehbein pull-through procedure. Complete removal was proved by clinical course and scintigraphy.

Abdomen, Acute