Search PubMed⌕ Search

Biomedical subjects

J Manny

Publications and source records attributed to J Manny.

65 records · Page 4Linked to original sources
PubMed1976

Monitoring of intraoperative heparinization in vascular surgery.

In 15 patients undergoing aortofemoral bypass, partial thromboplastin time (PTT) tests before and following intravenous administration of 75 U. per kilogram of heparin at zero, 30, 60, 90, and 120 minutes were determined for study of control of anticoagulant adequacy. The results demonstrate clearly that this amount provides excellent protection against thrombosis without bleeding complications. For intraoperative assay of heparin level effectiveness, the PTT test is advised. This test showed that a value of 250 percent of control still existed 75 minutes following the administration of heparin.

Aged↗
PubMed1976

Hepatic inactivation of renin in the treatment of hyperreninemic hypertension.

The concept of the hepatic inactivation of renin secreted by the juxtaglomerular apparatuses of the ischemic kidney was used for reversal of hypertension in dogs. In three dogs, the left renal artery was constricted, and a significant and well established hyperreninemic hypertension was recorded. The performance of an end-to-end splenorenal shunt following renal artery constriction reversed the hyperreninemia and hypertension. Shunting of the renal venous drainage into the portal system prior to constriction of the main renal artery prevented, as demonstrated by the limited data available, the development of hyperreninemic hypertension.

Animals↗
PubMedDate not supplied

Spontaneous midesophageal rupture.

Spontaneous rupture of the esophagus is rare. To date, 17 such cases, including our patient, have been reported in the literature. We present a case of true spontaneous rupture that occurred during sleep. Because the correct diagnosis was made 36 h after the rupture, treatment consisted of surgical drainage only. The drainage was extrapleural, though a posterior mediastinal approach, thereby avoiding the complication of empyema. The paraesophageal abscess was repeatedly irrigated with povidone-iodine solution. The patient recovered after a long period--56 days--of hospitalization. The report includes a review of the signs and symptoms of esophageal perforation, the current mode of therapy, and some speculation on the pathogenesis of true spontaneous perforation.

Drainage↗