Search PubMed⌕ Search

Biomedical subjects

J Macfie

Publications and source records attributed to J Macfie.

44 records · Page 3Linked to original sources
PubMed1979

Anorectal Crohn's disease.

Four hundred and twenty-three patients with Crohn's disease have been reviewed, 48 of whom had isolated anorectal involvement--an incidence of 11.4 per cent. These patients were compared with 48 randomly selected and sex-matched cases who presented with isolated ileocolic disease. The age of the anorectal patients (53.6 +/- 18 years) was greater than that of the controls (34.2 +/- 12 years). The duration of follow-up was 6.0 +/- 4 years and 12.6 +/- 8 years respectively. Rectal bleeding, diarrhoea and perianal disease were more common in the anorectal group. Twenty-two patients (46 per cent) with anorectal disease and 40 (83 per cent) in the ileocolic group underwent definitive surgery. There were 4 (18 per cent) postoperative deaths in the anorectal group and none among the controls. The incidence of recurrence was lower among the anorectal patients (21 per cent) compared with the ileocolic group (40 per cent). However, the estimated probability of recurrence, based on the duration of follow-up, the number of deaths during follow-up and the actual incidence of recurrence, is similar in both groups.

Adolescent↗
PubMed1979

Experience with the Russian model 249 suture gun for anastomosis of the rectum.

The Russian Model 249 circular suturing device used for rectal anastomoses in 62 patients undergoing high or low anterior resection or colectomy and ileorectal anastomosis was technically easy to use. The 38 high anastomoses were all shown to be intact by a Gastrografin, meglucomine diatrigoate, enema study 14 days after the operation. Of the 24 low anastomoses, six demonstrated small, 5 to 10 millimeters, dehiscences, two of the latter being evident also upon clinical examination. At least six of the low anastomoses were made at levels too low for hand suture from the abdomen. In three patients, moderate hemorrhage from the anastomotic site during the first two or three days complicated the situation; in all, it ceased spontaneously. In two patients, strictures developed, one of which rectified itself once the fecal stream was restored to the rectum on closing the transverse colostomy, the other was submitted to instrumental dilation, perhaps unnecessarily. The Model 249 circular suturing device provides colorectal anastomoses that are at least as secure as those done by hand suture and, sometimes, enables an anastomosis to be made at a lower level than would be possible by the conventional suture technique through the abdomen. Bleeding from the anastomotic site and subsequent stricture formation are rare complications of this technique.

Colectomy↗
PubMed1977

The treatment of acute superficial abscesses: a prospective clinical trial.

A total of 219 acute superficial abscesses was treated. Patients were randomly allocated to one of four treatment groups--primary suture with or without antibiotics and free drainage with or without antibiotics. No difference could be detected between the groups in duration of healing time. Eleven per cent of all abscesses sutured recurred and antibiotics did not affect this rate. It is suggested that free drainage following incision and drainage is the safest treatment for the majority of abscesses. Antibiotics do not have any significant effect on healing time or recurrence and their routine use is not recommended.

Abscess↗
PubMed1977

The ultrasound diagnosis of rectus sheath haematoma.

Three cases of rectus sheath haematoma are presented in which the diagnosis was confirmed by the use of ultrasound. The aetiology and diagnosis of the disease are discussed and the use of ultrasonography in a disease with a previously low preoperative diagnostic rate is emphasized.

Abdominal Muscles↗
PubMedDate not supplied

Effect of intravenous nutrition, with glucose as the only calorie source, on muscle glycogen.

This study was undertaken to assess the clinical significance of changes in muscle glycogen in the calculation of the energy requirements of patients fed intravenously. The glycogen content of the vastus or rectus muscle of 27 ill surgical patients with serious complications of the gastrointestinal tract was determined before and after a course of intravenous nutrition with various quantities of glucose as the caloric source. The quantity of glycogen in muscle before intravenous nutrition for all patients was 37 +/- 23 mg/g dry muscle; this was increased significantly (p less than .01) to 69 +/- 44 mg/g dry muscle after 14 days of feeding. In 5 patients who received intravenous nutrition for another 2 weeks, the glycogen content of the vastus muscle increased from a mean value of 80 mg/g dry muscle on day 14 of feeding to 106 mg/g on day 28, but this was not significant. The administration of glucose is invariably associated with an increase in the stores of muscle glycogen but the calorie equivalent of this gain in glycogen is small and, by our calculations, is no more than 530 kcal over the 14 days. We suggest that this gain is small relative to the energy expenditure of this type of patient and is of little clinical significance in the determination of their calorie requirements.

Adult↗