J M Sugarman | Search PubMed

PubMed1989

Subgaleal abscess: an unusual presentation.

We report a case of subgaleal abscess formation in a 16-year-old boy with varicella and minor head trauma. He presented four weeks after injury with left-sided scalp swelling and periorbital edema. There was no break in the skin over the involved area. Diagnosis was made on the basis of prolonged swelling, an elevated erythrocyte sedimentation rate, and computed tomography that showed a subgaleal fluid collection. Aspirated material grew Group A beta-hemolytic Streptococcus. Subgaleal abscess formation without an overlying wound is previously unreported. Management of subgaleal abscess usually requires operative debridement and IV antibiotics. However, in our patient, needle aspiration and oral antibiotics sufficed.

Abscess↗

PubMed1984

Fatty acid transfer between multilamellar liposomes and fatty acid-binding proteins.

A simple experimental system was developed for studying the movement of long-chain fatty acids between multilamellar liposomes and soluble proteins capable of binding fatty acids. Oleic acid was incorporated into multilamellar liposomes containing cholesterol and egg yolk lecithin and incubated with albumin or hepatic fatty acid-binding protein. It was found that the fatty acid transferred from the liposomes to either protein rapidly and selectively under conditions where phospholipid and cholesterol transfer did not occur. More than 50% of the fatty acid contained within liposomes could become protein bound, suggesting that the fatty acid moved readily between and across phospholipid bilayers. Transfer was reduced at low pH, and this reduction appeared to result from decreased dissociation of the protonated fatty acid from the bilayer. Liposomes made with dimyristoyl or dipalmitoyl lecithin and containing 1 mol per cent palmitic acid were used to show the effect of temperature on fatty acid transfer. Transfer to either protein did not occur at temperatures where the liposomes were in a gel state but occurred rapidly at temperatures at or above the transition temperatures of the phospholipid used.

Carbon Radioisotopes↗

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The 4-C program.

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Child↗