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Biomedical subjects

J M Silva

Publications and source records attributed to J M Silva.

101 records · Page 6Linked to original sources
PubMedDate not supplied

A case of human rabies in the urban area of Ribeirã Preto, SP, Brazil.

A 39-year old male patient was admitted to the University Hospital of the Faculty of Medicine of Ribeirão, Preto with signs and symptoms of sudden dyspnea, generalized myalgia and behavioral disorders. The initial suspicion was alcohol abstinence syndrome and the patient was referred for psychiatric and neurologic care. The evolution of the patient with a worsening of signs and symptoms, presence of crises of tachypnea, agitation, difficulty to swallow, irritability and hydrophobia, and his report of having been bitten by a suspected dog raised the hypothesis of rabies. The diagnosis was confirmed by examination of a corneal impression, biological tests in the cerebrospinal fluid (CSF) and saliva and visualization of Negri bodies in nervous tissue (direct immunofluorescence). The patient evolved with agitation, aggressiveness, and worsening tachypnea intercalating with apnea, and died on the 4th day after admission.

Adult↗
PubMedDate not supplied

[Hypertension: retrospective study in children from a pediatric nephrology unit].

300 hypertensive children, from newborn to 18 years old,were studied, retrospectively, from 1975 to 1992, 105 from those lost for follow-up. In 244 the diagnosis of the primary disease, predominantly glomerulopathy, was established. 122 had chronic renal failure (CRF). From them, 74 arrived at end stage renal disease (ESRD) and 13 have been transplanted. From 12 submitted to surgical treatment, hypertension has been controlled in 8. 54 died, 48 with CRF and 38 with ESRD. Difficulties in controlling those patients are discussed, mainly therapy diet, the use of hypotensive drugs on dialysis treatment. Our conclusion is for the necessity of a precocious diagnosis for hypertension and primary diseases, of a trained interprofessional team as well as availability of adequate equipment to children, mainly for dialytic therapy. For many of these children, renal transplantation is the only definite therapy.

English Abstract↗
PubMedDate not supplied

[Hepatic markers in a population of tavern customers].

We undertook this study to determine the prevalence of hepatic enzymes alterations in ambulant and healthy daily consumers of alcoholic beverages. In order to achieve this aim, a population of 107 regular customers from Coimbra's taverns was utilised. The percentage of results above the reference values was: Alk. Ph.-0%, AST/ALT--10.3%, T. Bil.--18.7%, ALT--37.4%, AST--44.9%, D. Bil.--52.3%, GGT--54.2%, GIDH--55.8%; seven individuals had normal levels of all hepatic markers, seventeen had 1 altered parameter, twenty two had 2, fourteen had 3, fifteen had 4, twenty had 5, eleven had 6, and one had 7. However, most of the alterations occur to levels close to normality. The correlation with the doses of alcohol is positive but low for all studied parameters, being statistically significant for some of them. The main conclusion of the present work is the demonstration that almost all tavern customers may already have disturbances of their hepatic biochemistry, though they look healthy, what represents an important and serious Public Health problem.

Adult↗