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Biomedical subjects

J M Rosene

Publications and source records attributed to J M Rosene.

3 recordsLinked to original sources
PubMed1999

Anterior tibial translation in collegiate athletes with normal anterior cruciate ligament integrity.

OBJECTIVE: To examine differences in anterior tibial translation (ATT) among sports, sex, and leg dominance in collegiate athletes with normal anterior cruciate ligament integrity. DESIGN AND SETTING: Subjects from various athletic teams were measured for ATT in right and left knees. SUBJECTS: Sixty subjects were measured for ATT with a KT-1000 knee arthrometer. MEASUREMENTS: Statistical analyses were computed for each sex and included a 2 x 3 x 4 mixed-factorial analysis of variance (ANOVA) for anterior cruciate ligament displacement, right and left sides, and force and sport. A 2 x 2 x 3 mixed-factorial ANOVA was computed to compare means for sex and force. A 2 x 3 mixed-factorial ANOVA was computed to compare sex differences across 3 forces. RESULTS: For males and females, no significant interactions were found among leg, force, and sport for mean ATT, for leg and sport or leg and force, or for translation values between dominant and nondominant legs. Males had a significant interaction for force and sport, and a significant difference was found for side of body, since the right side had less translation than the left side. Females had greater ATT than males at all forces. CONCLUSIONS: Sex differences exist for ATT, and differences in ATT exist among sports for both sexes. Differences between the right and left sides of the body should be expected when making comparisons of ligamentous laxity.

Journal Article↗
PubMed1999

Decongestant effects on hemodynamics at rest, exercise, and recovery from exercise during--6 degrees of head down tilt.

HYPOTHESIS: Ten males were studied to examine the effects of a decongestant, pseudoephedrine hydrochloride, on rest, exercise, and recovery from exercise during -6 degrees of head down tilt (HDT). METHODS: Subjects were positioned in the HDT for a total of 6 hr: 2 hr 45 min rest, 30 min exercise, and 2 hr 45 min recovery. Sessions were identical except for the ingestion of a drug or placebo. Variables evaluated during rest, exercise, and recovery conditions were: systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), stroke volume (SV), cardiac output (Q), pulse pressure (PP), mean arterial pressure (MAP), total peripheral resistance (TPR), and forearm blood flow (FBF). RESULTS: During rest PP at 120 min was less than resting baseline, and MAP increased throughout rest. There was a treatment effect for SBP which increased up to 90 min from resting baseline for the placebo treatment only. Normal changes were found with exercise, with all variables increasing above baseline except for TPR which decreased. DBP showed no change during exercise. During the recovery condition for the drug treatment HR decreased, while SBP increased from 30 min. In addition, DBP and MAP were higher for the placebo at 30 min and higher for the drug at 90 min. CONCLUSION: The results show that ingestion of the sympathomimetic agent pseudoephedrine hydrochloride has no significant effects on the cardiovascular system during simulated microgravity.

Adult↗