Baron Constantin von Economo and encephalitis lethargica.
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Biomedical subjects
Publications and source records attributed to J M Pearce.
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In 4 experiments, the authors used rats to examine the strength of responding during a clicker-tone compound in the presence of a light, after the auditory stimuli had individually been paired with food in the presence of the same light. Experiment 1 demonstrated a higher rate of responding during the compound when the duration of the light was short rather than long. In Experiments 2, 3, and 4, the long duration light was used as a signal for food in a conditional discrimination involving the tone and the clicker. Responding on test trials with the clicker-tone compound during the light was enhanced by this treatment and resulted in a level of performance that was no different from that observed when the duration of the light was short. The results are more compatible with a configural than an elemental theory of associative learning.
Cervicogenic headache describes pain referred along the upper three cervical roots and is a common source of headache in the over fifties. A review of clinical features, anatomy, and investigations using neural blockade shows several clinical pictures. Diseases of the cranio-vertebral junction, e.g. syringomyelia, and tonsilar descent, can produce mechanical or hydrodynamic head and neck pain. Pre-existent migraine and tension headache may be precipitated or aggravated by cervical spondylosis, but the anatomical mechanism is unclear. Headaches which arise from and are primarily caused by disorders in the cervical spine are exemplified by spondylosis and acute whiplash injury, but are usually transient. Evidence for a cervicogenic mechanism of chronic whiplash headache is, however, lacking.
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