Search PubMed⌕ Search

Biomedical subjects

J M Mukiibi

Publications and source records attributed to J M Mukiibi.

At least 37 records · Page 2Linked to original sources

Pattern of multiple myeloma in Kenyans.

A study of 75 myeloma patients diagnosed at the Kenyatta National Hospital, Nairobi, is presented. The male to female ratio was 1.7:1; the mean age +/- s.d. was 51.5 +/- 12.5 (range 16-80) years; the peak age incidence of 32% occurred in the sixth decade. A combination of: anaemia (81.3%), osteolytic lesions on X-ray skeletal survey (80%), bone pains (66.7%) and an ESR above 50mm/hr (77.3%) formed an important diagnostic tetrad. Other significant findings included: hypoalbuminaemia (76%), elevated leukocyte alkaline phosphatase (61.3%), uraemia (54.7%), upper respiratory tract infections (44%), elevated serum creatinine (34.7%), raised alkaline phosphatase (33.3%), pathological fractures (32%), hyperuricaemia (30.7%) and hypercalcaemia (29.3). The study confirms that the disease is not infrequent in indigenous Kenyan Africans as previous literature seemed to suggest. Poor prognosis was significantly (p less than 0.05) associated with hypoalbuminaemia, raised serum blood urea, hyperuricaemia and an elevated serum creatinine level.

Adolescent↗

Chronic idiopathic thrombocytopenic purpura (ITP) in Kenyan Africans.

Forty-two African patients with chronic idiopathic thrombocytopenic purpura (ITP) seen at the Kenyatta National Hospital, Nairobi, Kenya between June 1975 and June 1981 were used in this study. The disease appears to behave no differently from that in Western populations with regard to clinical and haematological features. Specific problems related to the disease in an African setting and the clinical significance of recognizing the disorder especially in a tropical environment are briefly pointed out.

Adolescent↗